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MIRAGE
Mannose-specific lectin

Summary
Lectin Name Aliases
  • GNA
  • GNL
  • Galanthus Nivalis Agglutinin
Monosaccharide Specificities
  • Man
Organism
Galanthus nivalis (common snowdrop)
UniProt
P30617
LfDB
UniLectin
P30617
CarboGrove
Annotation
Keyword
  • 3D-structure
  • Antiviral protein
  • Direct protein sequencing
  • Disulfide bond
  • Mannose-binding
  • Plant defense
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying 1 entry
GO Term
extracellular region
Displaying 1 entry
GO Term
mannose binding
Annotation information from UniProt.
Reference
Displaying all 5 entries
PubMed ID Title First Author
3335522 Binding properties of a mannose-specific lectin from the snowdrop (Galanthus nivalis) bulb. Shibuya N
15814822 Mammalian-like nonsialyl complex-type N-glycosylation of equine gonadotropins in Mimic insect cells. Legardinier S
20507987 Microvirin, a novel alpha(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of cyanovirin-N but a much higher safety profile. Huskens D
27558840 High-resolution crystal structures of Colocasia esculenta tarin lectin. Pereira PR
32763972 Point mutations that inactivate MGAT4D-L, an inhibitor of MGAT1 and complex N-glycan synthesis. Akintayo A
Lectin Frontier DataBase (LfDB)
GlyTouCan
G77712UR
V-V0
52.59
GlyTouCan
G67816CZ
V-V0
43.14
GlyTouCan
G62167DK
V-V0
42.72
LfDB provides quantitative interaction data in terms of the affinity constants (Ka) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.
MCAW
The MCAW profile of the top three glycans above, which resulted from FAC analysis.
UniLectin
UniProt
P30617
CarboGrove
Lectin Name
Galanthus Nivalis Agglutinin
Common Name
GNA
Automated Analysis report (Top 10 high affinity glycans)
Array Source
ASYMN
Protein Source
EY Labs
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G07483YN
3937.5 258.91
G61751GZ
2702.67 97.69
G69411IG
1905.17 126.32
G64481DJ
1813.5 208.94
G28663KH
810.5 80.99
G10133VD
778.33 77.46
G30131YB
459 17.89
G55220VL
364.33 59.08
G89036WC
310.33 34.4
G06209KS
219.67 17.11

GlyTouCan ID Binding Intensity Stdev
G64481DJ
11170.83 698.91
G07483YN
10683.67 432.75
G61751GZ
9217 653.81
G69411IG
7758.5 309.84
G28663KH
7542 910.14
G10133VD
4561.33 481.57
G55220VL
4186 482.08
G30131YB
3403 288.38
G89036WC
2942.17 181.96
G06209KS
2657.67 160.61

GlyTouCan ID Binding Intensity Stdev
G64481DJ
18433.17 2387.89
G28663KH
17779 416.88
G07483YN
16930.67 590.2
G61751GZ
15518.17 1030.48
G69411IG
15229.5 1327.95
G10133VD
11545.67 766.25
G55220VL
11043.5 715.02
G30131YB
9665.5 1313.36
G06209KS
8735.67 448.33
G66937TJ
8612.33 506.86
CarboGrove View
Array Source
CFG
Protein Source
EY Labs
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G22768VO
1645.93 173.03
G80966KZ
1370.57 46.61
G82348BZ
673.81 34.37
G18320HP
478.54 40.24
G55220VL
466.57 83.43
G00619DD
462.99 57.09
G24095BS
446.78 48.1
G17779DH
376.36 26.31
G23046QV
353.75 54.57
G22768VO
334.15 15.29

GlyTouCan ID Binding Intensity Stdev
G22768VO
19148.8 1868.86
G22768VO
7089.36 456.66
G55220VL
5263.72 477
G80966KZ
4872.25 432.55
G82348BZ
4715.25 589.7
G00619DD
2750.05 322.15
G23046QV
2302.95 200.4
G52724WY
2178 184.06
G69411IG
2032.74 235.49
G28663KH
1965.19 110.26

GlyTouCan ID Binding Intensity Stdev
G22768VO
29378.7 1542.56
G52724WY
17500.34 519.66
G22768VO
15358.74 1268.51
G80966KZ
14581.94 799.55
G55220VL
13790.18 971.51
G00619DD
12280.15 1225.98
G69411IG
12120.82 673.2
G82348BZ
11714.08 566.49
G39213VZ
10517.55 617.55
G23046QV
10329.65 408.34

GlyTouCan ID Binding Intensity Stdev
G22768VO
32454.44 353.09
G52724WY
29411.5 928.51
G39213VZ
27859 622.81
G22768VO
24832.09 1102.66
G13773HT
24273.92 1398.6
G69411IG
24062.26 2154.38
G00619DD
23136.4 983.96
G05260RH
22980.45 1110.93
G80966KZ
22676.32 2371.5
G55220VL
21057.99 1143.73
CarboGrove View
Array Source
CFG
Protein Source
Sigma
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G22768VO
11802.14 483.47
G82348BZ
6077.55 212.56
G22768VO
5832.54 324.96
G28663KH
5829.2 531.23
G55220VL
4371.06 263.2
G31865AG
4128.31 279.78
G80966KZ
4049.48 198.98
G65997KL
3905.72 306.76
G23046QV
3895.59 198.3
G63337SS
3318.64 169.68
CarboGrove View
Array Source
ASNLinked
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G03652TR
19833 4755
G22768VO
11609 619
G91413ZX
2132 867
G94531EZ
1981 492
G78059CC
1765 64
G56318NV
1202 817
G80858MF
1201 78
G78030KJ
1168 885
G17689DH
1121 450
G28800UK
1001 261

GlyTouCan ID Binding Intensity Stdev
G03652TR
26114.25 2528.68
G22768VO
15463.5 1186.7
G78059CC
5343 140.04
G80858MF
3066 210.34
G36191CD
2866.75 457.29
G91413ZX
2518.5 1051.33
G86357DX
2236.5 318.03
G94531EZ
2197 660.35
G39213VZ
1675 267.45
G56318NV
1422.75 975.89
CarboGrove View
Array Source
CFG
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G22768VO
2563.79 77.91
G22768VO
2108.5 88.96
G82348BZ
1432.82 158.69
G80966KZ
1127.93 138.72
G55220VL
950.86 147.69
G17779DH
513.51 43.04
G63337SS
490.23 288.85
G18320HP
357.29 16.31
G24095BS
298.87 81.8
G23046QV
260.13 87.52

GlyTouCan ID Binding Intensity Stdev
G22768VO
11387.79 285.74
G82348BZ
5031.88 184.36
G22768VO
4981.82 251.69
G55220VL
3404.93 126.5
G80966KZ
3085.41 544.15
G23046QV
1473.3 88.64
G63337SS
1236.06 216.74
G00619DD
981.6 241.13
G17779DH
474.47 17.77
G18320HP
449.96 27.99

GlyTouCan ID Binding Intensity Stdev
G22768VO
10184.03 1848.41
G82348BZ
6797.76 1696.46
G22768VO
6299.79 473.19
G80966KZ
5174.2 324.52
G55220VL
4975.37 372.17
G23046QV
3014.54 173.35
G63337SS
2826.84 371.29
G00619DD
2313.45 184.12
G28663KH
1784.93 153.11
G17779DH
762.31 37.9

GlyTouCan ID Binding Intensity Stdev
G22768VO
14340.35 2981.61
G22768VO
7924.79 357.32
G82348BZ
6134.93 302.28
G00619DD
4671.68 473.08
G55220VL
4096.25 360.37
G80966KZ
3562.29 545.58
G23046QV
2880 124.84
G52724WY
2850 114.11
G39213VZ
2448.14 28.04
G69411IG
2351.45 131.05
CarboGrove View
Array Source
NCFG
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G22768VO
34376 3667
G22768VO
27697 3957
G55220VL
26946 1889
G82348BZ
21614 3487
G28663KH
9289 819
G23046QV
8595 1762
G80966KZ
7769 350
G00619DD
4070 682
G31865AG
3806 599
G65997KL
2819 394

GlyTouCan ID Binding Intensity Stdev
G22768VO
34422 4601
G28663KH
31509 1717
G55220VL
30098 3320
G80966KZ
28538 1898
G23046QV
27244 3490
G22768VO
26683 1230
G82348BZ
23896 4746
G00619DD
17143 1119
G31865AG
15554 3458
G52724WY
9604 733
CarboGrove View
Array Source
ZBiotech
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G03652TR
65452.83 0
G19747OA
55108.5 0
G65984FE
31371.5 0
G38297TU
27934.16 0
G88876JQ
24151.83 0
G29024OJ
23611.66 0
G44747CU
18057.33 0
G86053IC
12423.83 0
G86053IC
9967.83 0
G66741YQ
3643 0
CarboGrove View
Array Source
ZBiotech
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G03652TR
28928.5 266.58
G19747OA
17261.5 331.63
G56202TA
17251 2289.61
G51964GO
5797 11.31
G81262CB
104.25 86.62
G07490EK
63 2.83
G70323CJ
61.25 0.35
G49963IQ
56.5 0.71
G29313LW
55 5.66
G64581RP
54.5 0.71
CarboGrove View
CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.
PDB
1JPC
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
1MSA
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
1NIV
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025