GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	June 6, 2024
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **276 - 298** of **298** in total

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GlyCosmos Lectin ▲	Lectin Name	UniProt ID	PDB IDs	Organism	Taxonomy ID	Gene Ontology	Gene Ontology ID
GL_004645	Dolichol-phosphate mannosyltransferase subunit 1	O60762		Homo sapiens (human)	9606	GDP-mannose metabolic process GPI anchor biosynthetic process alcohol binding dolichol metabolic process dolichol-linked oligosaccharide biosynthetic process dolichol-phosphate-mannose synthase complex dolichyl-phosphate beta-D-mannosyltransferase activity dolichyl-phosphate-mannose-protein mannosyltransferase activity endoplasmic reticulum membrane endoplasmic reticulum mannose binding membrane metal ion binding nucleus protein N-linked glycosylation via asparagine protein O-linked mannosylation protein mannosylation	GO:0004169 GO:0004582 GO:0005537 GO:0005634 GO:0005783 GO:0005789 GO:0006488 GO:0006506 GO:0016020 GO:0018279 GO:0019348 GO:0019673 GO:0033185 GO:0035268 GO:0035269 GO:0043178 GO:0046872
GL_004706	Putative inactive beta-glucuronidase-like protein SMA3	Q15486		Homo sapiens (human)	9606	beta-glucuronidase activity carbohydrate binding extracellular space glucuronoside catabolic process nervous system development signaling receptor binding skeletal system development	GO:0001501 GO:0004566 GO:0005102 GO:0005615 GO:0007399 GO:0019391 GO:0030246
GL_004815	Putative inactive beta-glucuronidase protein GUSBP11	Q6P575		Homo sapiens (human)	9606	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process extracellular space glucuronoside catabolic process signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005975 GO:0019391 GO:0030246
GL_004899	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	Q96Q83	2IUW 8JNK 8JNR	Homo sapiens (human)	9606	DNA dealkylation involved in DNA repair DNA repair L-ascorbic acid binding cell population proliferation cytosol ferrous iron binding mRNA N1-methyladenosine dioxygenase activity mitochondrion nucleoplasm nucleus oxidative DNA demethylase activity oxidative RNA demethylase activity oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation	GO:0005634 GO:0005654 GO:0005739 GO:0005829 GO:0006281 GO:0006307 GO:0008198 GO:0008283 GO:0031418 GO:0035515 GO:0035516 GO:0035552 GO:0035553 GO:1990930
GL_004920	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3	Q6PK18		Homo sapiens (human)	9606	L-ascorbic acid binding dioxygenase activity iron ion binding membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0005506 GO:0016020 GO:0016705 GO:0031418 GO:0051213
GL_004926	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	O00469		Homo sapiens (human)	9606	L-ascorbic acid binding endoplasmic reticulum membrane endoplasmic reticulum extracellular exosome hydroxylysine biosynthetic process iron ion binding peptidyl-lysine hydroxylation procollagen-lysine 5-dioxygenase activity protein modification process response to hypoxia rough endoplasmic reticulum membrane	GO:0001666 GO:0005506 GO:0005783 GO:0005789 GO:0008475 GO:0017185 GO:0030867 GO:0031418 GO:0036211 GO:0046947 GO:0070062
GL_004944	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2	Q6N063		Homo sapiens (human)	9606	L-ascorbic acid binding dioxygenase activity iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0005506 GO:0016705 GO:0031418 GO:0051213
GL_004965	Dopamine beta-hydroxylase	P09172	4ZEL	Homo sapiens (human)	9606	L-ascorbic acid binding behavioral response to ethanol blood vessel remodeling catalytic activity centriolar satellite chemical synaptic transmission chromaffin granule lumen chromaffin granule membrane copper ion binding cytoplasm dopamine beta-monooxygenase activity dopamine catabolic process endoplasmic reticulum extracellular region extracellular space fear response glucose homeostasis homoiothermy intracellular membrane-bounded organelle leukocyte mediated immunity leukocyte migration locomotory behavior maternal behavior membrane memory norepinephrine biosynthetic process octopamine biosynthetic process positive regulation of cold-induced thermogenesis positive regulation of vasoconstriction regulation of extrinsic apoptotic signaling pathway regulation of vascular associated smooth muscle cell proliferation regulation of vascular endothelial cell proliferation response to amphetamine response to pain secretory granule lumen secretory granule membrane synapse transport vesicle membrane vasoconstriction visual learning	GO:0001974 GO:0001975 GO:0002443 GO:0003824 GO:0004500 GO:0005507 GO:0005576 GO:0005615 GO:0005737 GO:0005783 GO:0006589 GO:0007268 GO:0007613 GO:0007626 GO:0008542 GO:0016020 GO:0030658 GO:0030667 GO:0031418 GO:0034451 GO:0034466 GO:0034774 GO:0042309 GO:0042310 GO:0042420 GO:0042421 GO:0042584 GO:0042593 GO:0042596 GO:0042711 GO:0043231 GO:0045202 GO:0045907 GO:0048149 GO:0048265 GO:0050900 GO:0120162 GO:1904705 GO:1905562 GO:2001236
GL_004978	Egl nine homolog 1	Q9GZT9	2G19 2G1M 2HBT 2HBU 2Y33 2Y34 3HQR 3HQU 3OUH 3OUI 3OUJ 4BQW 4BQX 4BQY 4JZR 4KBZ 4UWD 5A3U 5L9B 5L9R 5L9V 5LA9 5LAS 5LAT 5LB6 5LBB 5LBC 5LBE 5LBF 5OX5 5OX6 5V18 6NMQ 6QGV 6ST3 6YVT 6YVW 6YVX 6YVZ 6YW0 6YW1 6YW2 6YW3 6YW4 6ZBN 6ZBO 7Q5V 7Q5X 7UJV 7UMP	Homo sapiens (human)	9606	2-oxoglutarate-dependent dioxygenase activity L-ascorbic acid binding cardiac muscle tissue morphogenesis cellular response to hypoxia cytoplasm cytosol enzyme binding ferrous iron binding glutamatergic synapse heart trabecula formation hypoxia-inducible factor-proline dioxygenase activity intracellular iron ion homeostasis intracellular membrane-bounded organelle intracellular oxygen homeostasis labyrinthine layer development negative regulation of DNA-binding transcription factor activity negative regulation of cyclic-nucleotide phosphodiesterase activity nucleus peptidyl-proline 4-dioxygenase activity peptidyl-proline dioxygenase activity peptidyl-proline hydroxylation to 4-hydroxy-L-proline positive regulation of transcription by RNA polymerase II postsynaptic density regulation of angiogenesis regulation of modification of postsynaptic structure regulation protein catabolic process at postsynapse response to hypoxia response to nitric oxide ventricular septum morphogenesis	GO:0001666 GO:0005634 GO:0005737 GO:0005829 GO:0006879 GO:0008198 GO:0014069 GO:0016706 GO:0018401 GO:0019899 GO:0031418 GO:0031543 GO:0031545 GO:0032364 GO:0043231 GO:0043433 GO:0045765 GO:0045944 GO:0051344 GO:0055008 GO:0060347 GO:0060412 GO:0060711 GO:0071456 GO:0071731 GO:0098978 GO:0099159 GO:0140252 GO:0160082
GL_004979	Prolyl 3-hydroxylase 1	Q32P28		Homo sapiens (human)	9606	L-ascorbic acid binding bone development chaperone-mediated protein folding collagen metabolic process cytoplasm endoplasmic reticulum lumen endoplasmic reticulum extracellular exosome iron ion binding membrane negative regulation of cell population proliferation negative regulation of post-translational protein modification nucleus positive regulation of neuron projection development procollagen-proline 3-dioxygenase activity protein folding protein hydroxylation protein stabilization protein-containing complex regulation of protein secretion	GO:0005506 GO:0005634 GO:0005737 GO:0005783 GO:0005788 GO:0006457 GO:0008285 GO:0010976 GO:0016020 GO:0018126 GO:0019797 GO:0031418 GO:0032963 GO:0032991 GO:0050708 GO:0050821 GO:0060348 GO:0061077 GO:0070062 GO:1901874
GL_005016	Prolyl hydroxylase EGLN2	Q96KS0	5V1B	Homo sapiens (human)	9606	2-oxoglutarate-dependent dioxygenase activity L-ascorbic acid binding cell redox homeostasis cellular response to hypoxia cytoplasm ferrous iron binding hypoxia-inducible factor-proline dioxygenase activity intracellular estrogen receptor signaling pathway nucleoplasm nucleus oxygen sensor activity peptidyl-proline 4-dioxygenase activity peptidyl-proline hydroxylation to 4-hydroxy-L-proline positive regulation of protein catabolic process regulation of cell growth regulation of neuron apoptotic process response to hypoxia	GO:0001558 GO:0001666 GO:0005634 GO:0005654 GO:0005737 GO:0008198 GO:0016706 GO:0018401 GO:0019826 GO:0030520 GO:0031418 GO:0031545 GO:0043523 GO:0045454 GO:0045732 GO:0071456 GO:0160082
GL_005069	Phytanoyl-CoA dioxygenase, peroxisomal	O14832	2A1X	Homo sapiens (human)	9606	2-oxobutyrate catabolic process 2-oxoglutarate metabolic process 9+0 non-motile cilium L-ascorbic acid binding carboxylic acid binding cytosol fatty acid alpha-oxidation ferrous iron binding isoprenoid metabolic process methyl-branched fatty acid metabolic process peroxisomal matrix peroxisome phytanoyl-CoA dioxygenase activity	GO:0001561 GO:0005777 GO:0005782 GO:0005829 GO:0006103 GO:0006720 GO:0008198 GO:0019606 GO:0031406 GO:0031418 GO:0048244 GO:0097089 GO:0097731
GL_005071	Prolyl 3-hydroxylase OGFOD1	Q8N543	4NHX 4NHY	Homo sapiens (human)	9606	L-ascorbic acid binding cell population proliferation cytoplasm cytoplasmic stress granule cytosol iron ion binding nucleoplasm peptidyl-proline 3-dioxygenase activity peptidyl-proline dioxygenase activity peptidyl-proline hydroxylation protein hydroxylation regulation of translational termination stress granule assembly	GO:0005506 GO:0005654 GO:0005737 GO:0005829 GO:0006449 GO:0008283 GO:0010494 GO:0018126 GO:0019511 GO:0031418 GO:0031543 GO:0031544 GO:0034063
GL_005093	Prolyl 3-hydroxylase 2	Q8IVL5		Homo sapiens (human)	9606	Golgi apparatus L-ascorbic acid binding basement membrane collagen metabolic process cytosol endoplasmic reticulum lumen endoplasmic reticulum intracellular membrane-bounded organelle iron ion binding negative regulation of cell population proliferation nucleoplasm peptidyl-proline hydroxylation procollagen-proline 3-dioxygenase activity sarcoplasmic reticulum	GO:0005506 GO:0005604 GO:0005654 GO:0005783 GO:0005788 GO:0005794 GO:0005829 GO:0008285 GO:0016529 GO:0019511 GO:0019797 GO:0031418 GO:0032963 GO:0043231
GL_005117	Transmembrane prolyl 4-hydroxylase	Q9NXG6	6TP5	Homo sapiens (human)	9606	2-oxoglutarate-dependent dioxygenase activity L-ascorbic acid binding calcium ion binding endoplasmic reticulum membrane endoplasmic reticulum hypoxia-inducible factor-proline dioxygenase activity iron ion binding procollagen-proline 4-dioxygenase activity regulation of erythrocyte differentiation	GO:0004656 GO:0005506 GO:0005509 GO:0005783 GO:0005789 GO:0016706 GO:0031418 GO:0045646 GO:0160082
GL_005149	Prolyl 4-hydroxylase subunit alpha-2	O15460	6EVL 6EVM 6EVN 6EVO 6EVP 7ZSC	Homo sapiens (human)	9606	L-ascorbic acid binding cytosol electron transfer activity endoplasmic reticulum lumen endoplasmic reticulum intracellular membrane-bounded organelle iron ion binding nucleoplasm procollagen-proline 4-dioxygenase activity	GO:0004656 GO:0005506 GO:0005654 GO:0005783 GO:0005788 GO:0005829 GO:0009055 GO:0031418 GO:0043231
GL_005165	Peptidyl-glycine alpha-amidating monooxygenase	P19021		Homo sapiens (human)	9606	L-ascorbic acid binding calcium ion binding copper ion binding extracellular exosome extracellular region fatty acid primary amide biosynthetic process membrane peptide amidation peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity response to zinc ion secretory granule membrane transport vesicle membrane zinc ion binding	GO:0001519 GO:0004504 GO:0004598 GO:0005507 GO:0005509 GO:0005576 GO:0008270 GO:0010043 GO:0016020 GO:0030658 GO:0030667 GO:0031418 GO:0062112 GO:0070062
GL_005175	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	O60568	6FXK 6FXM 6FXR 6FXT 6FXX 6FXY 6TE3 6TEC 6TES 6TEU 6TEX 6TEZ 6WFV 8ONE	Homo sapiens (human)	9606	Golgi apparatus L-ascorbic acid binding basement membrane assembly collagen fibril organization collagen metabolic process collagen-containing extracellular matrix endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum endothelial cell morphogenesis epidermis morphogenesis extracellular exosome extracellular space hydroxylysine biosynthetic process in utero embryonic development iron ion binding lung morphogenesis metal ion binding neural tube development peptidyl-lysine hydroxylation procollagen galactosyltransferase activity procollagen glucosyltransferase activity procollagen-lysine 5-dioxygenase activity protein O-linked glycosylation protein localization rough endoplasmic reticulum small molecule binding trans-Golgi network vasodilation	GO:0001701 GO:0001886 GO:0005506 GO:0005615 GO:0005783 GO:0005788 GO:0005789 GO:0005791 GO:0005794 GO:0005802 GO:0006493 GO:0008104 GO:0008475 GO:0017185 GO:0021915 GO:0030199 GO:0031418 GO:0032963 GO:0033823 GO:0036094 GO:0042311 GO:0046872 GO:0046947 GO:0048730 GO:0050211 GO:0060425 GO:0062023 GO:0070062 GO:0070831
GL_005179	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	Q02809		Homo sapiens (human)	9606	L-ascorbic acid binding catalytic complex endoplasmic reticulum membrane endoplasmic reticulum epidermis development extracellular exosome iron ion binding peptidyl-lysine hydroxylation procollagen-lysine 5-dioxygenase activity response to hypoxia rough endoplasmic reticulum membrane	GO:0001666 GO:0005506 GO:0005783 GO:0005789 GO:0008475 GO:0008544 GO:0017185 GO:0030867 GO:0031418 GO:0070062 GO:1902494
GL_005207	Prolyl 4-hydroxylase subunit alpha-1	P13674	1TJC 2V5F 2YQ8 4BT8 4BT9 4BTA 4BTB	Homo sapiens (human)	9606	L-ascorbic acid binding collagen fibril organization endoplasmic reticulum lumen endoplasmic reticulum identical protein binding intracellular membrane-bounded organelle iron ion binding membrane mitochondrion procollagen-proline 4-dioxygenase activity procollagen-proline 4-dioxygenase complex	GO:0004656 GO:0005506 GO:0005739 GO:0005783 GO:0005788 GO:0016020 GO:0016222 GO:0030199 GO:0031418 GO:0042802 GO:0043231
GL_005235	Prolyl 3-hydroxylase 3	Q8IVL6		Homo sapiens (human)	9606	L-ascorbic acid binding catalytic complex collagen biosynthetic process collagen metabolic process endoplasmic reticulum iron ion binding negative regulation of cell population proliferation peptidyl-lysine hydroxylation procollagen-proline 3-dioxygenase activity	GO:0005506 GO:0005783 GO:0008285 GO:0017185 GO:0019797 GO:0031418 GO:0032963 GO:0032964 GO:1902494
GL_005250	Prolyl hydroxylase EGLN3	Q9H6Z9		Homo sapiens (human)	9606	2-oxoglutarate-dependent dioxygenase activity DNA damage response L-ascorbic acid binding activation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic process cellular response to hypoxia cytoplasm cytosol ferrous iron binding hypoxia-inducible factor-proline dioxygenase activity nucleoplasm nucleus peptidyl-proline 4-dioxygenase activity peptidyl-proline hydroxylation to 4-hydroxy-L-proline protein hydroxylation regulation of cell population proliferation regulation of neuron apoptotic process response to hypoxia	GO:0001666 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006915 GO:0006919 GO:0006974 GO:0008198 GO:0016706 GO:0018126 GO:0018401 GO:0031418 GO:0031545 GO:0042127 GO:0043523 GO:0071456 GO:0160082
GL_005280	Prolyl 4-hydroxylase subunit alpha-3	Q7Z4N8		Homo sapiens (human)	9606	L-ascorbic acid binding endoplasmic reticulum lumen endoplasmic reticulum iron ion binding procollagen-proline 4-dioxygenase activity	GO:0004656 GO:0005506 GO:0005783 GO:0005788 GO:0031418

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