GlyCosmos Portal

Canis familiaris (dog)

Summary

Taxonomy ID: 9615
PubChem Taxonomy: 9615

Genes (1237) Glycans (57) Glycoproteins (493) Lectins (17) Pathways (268)

Displaying entries **101 - 125** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	78 kDa glucose-regulated protein ABC-type antigen peptide transporter Aminopeptidase Beta-2-microglobulin Calnexin Calreticulin GTP-binding protein SAR1b Immunoglobulin C1-set domain-containing protein MHC class I DLA-12 MHC class I DLA-64 MHC class I DLA-88 MHC class Ib Protein SEC13 homolog Protein disulfide-isomerase Protein transport protein SEC23 Protein transport protein Sec31A SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Tapasin	A0A8I3MLY2 A0A8I3N796 A0A8I3N9C4 A0A8I3NCJ5 A0A8I3NCT5 A0A8I3NDA5 A0A8I3NM03 A0A8I3NPS2 A0A8I3NRG2 A0A8I3NSU2 A0A8I3NZH7 A0A8I3P4F9 A0A8I3P4Y2 A0A8I3PXH7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RUA9 A0A8I3S449 A0A8I3S5M8 A0A8I3SCF9 Q5TJE4	B2M CALR CANX DLA-12 DLA-79 DLA-DOB DLA88 ERAP1 HSPA5 LOC119876190 LOC119876868 PDIA3 SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A TAPBP
COPII-mediated vesicle transport	Alpha 1 antitrypsin Ankyrin repeat domain 28 Bet1 golgi vesicular membrane trafficking protein Casein kinase I isoform delta Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein NSF attachment protein alpha NSF attachment protein beta Prolactin regulatory element-binding protein Protein SEC13 homolog Protein cornichon homolog 2 Protein phosphatase 6 regulatory subunit 1 Protein phosphatase 6 regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec31A Protein transport protein sec16 Protein transport protein sec16 Ras-related protein Rab-1A SEC22 homolog A, vesicle trafficking protein SEC22 homolog B, vesicle trafficking protein SEC22 homolog C, vesicle trafficking protein SEC23 interacting protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Sec1 family domain containing 1 Serine/threonine-protein phosphatase Syntaxin 17 Syntaxin 5 TBC1 domain family member 20 Trafficking from ER to golgi regulator Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Trafficking protein particle complex subunit Trafficking protein particle complex subunit Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Vesicle-fusing ATPase Vesicular integral-membrane protein VIP36 YKT6 v-SNARE homolog cathepsin X small monomeric GTPase	A0A8I3MAV2 A0A8I3MJ74 A0A8I3MLH1 A0A8I3MLQ0 A0A8I3MT73 A0A8I3MT80 A0A8I3MUS5 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3MZY0 A0A8I3N2I9 A0A8I3N5A8 A0A8I3N5C1 A0A8I3N796 A0A8I3N7P4 A0A8I3N9C4 A0A8I3N9V0 A0A8I3NBA1 A0A8I3NCZ9 A0A8I3NFJ9 A0A8I3NKE3 A0A8I3NPG4 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NX57 A0A8I3NYM5 A0A8I3NZH7 A0A8I3NZS8 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PAS9 A0A8I3PEN5 A0A8I3PNK8 A0A8I3PQR9 A0A8I3PTJ0 A0A8I3PTW0 A0A8I3PU34 A0A8I3PV59 A0A8I3PVF9 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q4E7 A0A8I3Q5G1 A0A8I3Q7H2 A0A8I3QC45 A0A8I3QS42 A0A8I3RR85 A0A8I3RRF7 A0A8I3RSX1 A0A8I3RU45 A0A8I3RUA0 A0A8I3RVH6 A0A8I3RWZ7 A0A8I3RZB2 A0A8I3S3N8 A0A8I3S444 A0A8I3S449 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 E2QV03 P49256 P62822	ANKRD28 AREG BET1 CD59 CNIH1 CNIH2 CNIH3 CSNK1D CTSC CTSZ F5 GOLGA2 GORASP1 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 NAPA NAPB NAPG NSF PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A SCFD1 SEC13 SEC16A SEC16B SEC22A SEC22C SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SERPINA1 STX17 STX5 TBC1D20 TFG TGFA TMED10 TMED2 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 USO1 YKT6
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase EF-hand domain-containing protein Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase C delta 4 Phospholipase C zeta 1 Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A8I3MH68 A0A8I3MSQ7 A0A8I3MYA9 A0A8I3N810 A0A8I3NFE2 A0A8I3NWQ5 A0A8I3NY96 A0A8I3NZG2 A0A8I3PAP4 A0A8I3PAT0 A0A8I3PB87 A0A8I3PC05 A0A8I3PFD9 A0A8I3PLP7 A0A8I3PN52 A0A8I3PQK7 A0A8I3Q2Q7 A0A8I3Q4W3 A0A8I3Q7I7 A0A8I3Q9F2 A0A8I3QSE4 A0A8I3S2X3 A0A8I3S6D4 A0A8I3S7X1 A0A8I3SCI7 P60483	CALM2 INPP5B INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKB ITPKC MMAC1 OCRL PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCZ1 PLD4 PTEN SHIP2 SYNJ1
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A8I3NBK6 A0A8I3NUU1 A0A8I3PT69 A0A8I3PWD4 A0A8I3S3D9 P01321	GRB10 GRB2 INS INSR SHC1 SOS1
Signaling by ROBO receptors	Glypican-1 Slit guidance ligand 2 Slit guidance ligand 3	A0A8I3MRE2 A0A8I3NQC4 A0A8I3Q4U0	GPC1 SLIT2 SLIT3
Tie2 Signaling	Angiopoietin 4 Angiopoietin-1 Angiopoietin-2 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 14 Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N971 A0A8I3NC50 A0A8I3NID0 A0A8I3NM36 A0A8I3NUU1 A0A8I3NZA4 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1A9 A0A8I3Q1I3 A0A8I3S0B4 A0A8I3S3D9 A0A8I3S3N2 A0A8J8	ANGPT1 ANGPT2 ANGPT4 DOK2 GRB14 GRB2 GRB7 HRAS KRAS NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PTPN11 SHC1 SOS1 TEK
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Gamma-glutamyltransferase 6 Glutathione S-transferase Glutathione S-transferase Glutathione hydrolase Glutathione hydrolase Glutathione transferase Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 N-acyl-aliphatic-L-amino acid amidohydrolase Sulfotransferase 1A1 Sulfotransferase Sulfotransferase glucuronosyltransferase glucuronosyltransferase glucuronosyltransferase	A0A8I3MEU4 A0A8I3MEX7 A0A8I3N072 A0A8I3N1I8 A0A8I3N279 A0A8I3N2I7 A0A8I3NBB4 A0A8I3NE83 A0A8I3P300 A0A8I3PHP8 A0A8I3PSW5 A0A8I3PVZ3 A0A8I3QRM6 A0A8I3QUB8 A0A8I3S0X8 A0A8I3S4W3 A0A8I3SCV5 B3RFJ1 B8K1W7 Q29476 Q6UR05 Q9MZY0	ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABHD14A Abcc4 Abcg2 CNDP2 CYP2E1 GGT1 GGT6 GGT7 GSTP1 LOC119874463 LOC119876946 MRP1 SULT1A1 SULT1C4 SULT1E1 UGT1A6
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase with thrombospondin type 1 motif 10 ADAM metallopeptidase with thrombospondin type 1 motif 12 ADAM metallopeptidase with thrombospondin type 1 motif 13 ADAM metallopeptidase with thrombospondin type 1 motif 14 ADAM metallopeptidase with thrombospondin type 1 motif 16 ADAM metallopeptidase with thrombospondin type 1 motif 17 ADAM metallopeptidase with thrombospondin type 1 motif 18 ADAM metallopeptidase with thrombospondin type 1 motif 19 ADAM metallopeptidase with thrombospondin type 1 motif 1 ADAM metallopeptidase with thrombospondin type 1 motif 20 ADAM metallopeptidase with thrombospondin type 1 motif 2 ADAM metallopeptidase with thrombospondin type 1 motif 3 ADAM metallopeptidase with thrombospondin type 1 motif 5 ADAM metallopeptidase with thrombospondin type 1 motif 6 ADAM metallopeptidase with thrombospondin type 1 motif 8 ADAM metallopeptidase with thrombospondin type 1 motif 9 ADAMTS like 1 ADAMTS like 2 ADAMTS like 4 Beta 3-glucosyltransferase Complement factor properdin GDP-fucose protein O-fucosyltransferase 2 NTR domain-containing protein SCO-spondin Semaphorin 5A Semaphorin 5B Somatomedin B and thrombospondin type 1 domain containing Spondin-1 Thrombospondin 1 Thrombospondin 2 Thrombospondin type 1 domain containing 7A Thrombospondin type 1 domain containing 7B Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A4D6CAB5 A0A8I3MD18 A0A8I3MIA8 A0A8I3MQ02 A0A8I3MRT7 A0A8I3MXQ6 A0A8I3MZ18 A0A8I3MZD5 A0A8I3N140 A0A8I3N1D3 A0A8I3N2T5 A0A8I3NA49 A0A8I3NAX6 A0A8I3NB75 A0A8I3NE19 A0A8I3NGS7 A0A8I3NK12 A0A8I3NKG0 A0A8I3NM21 A0A8I3NS78 A0A8I3P088 A0A8I3P1X0 A0A8I3P533 A0A8I3PA53 A0A8I3PBE9 A0A8I3PG52 A0A8I3PJ96 A0A8I3PJW2 A0A8I3PNR9 A0A8I3PPJ4 A0A8I3PPU8 A0A8I3PQZ5 A0A8I3PUQ0 A0A8I3Q3A2 A0A8I3Q4T9 A0A8I3Q9Y4 A0A8I3RTV1 A0A8I3S8L6	ADAMTS1 ADAMTS10 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL4 ADAMTSL5 B3GLCT CFP POFUT2 SBSPON SEMA5A SEMA5B SH3GL3 SPON1 SPON2 SSPO THBS1 THBS2 THSD1 THSD7A THSD7B
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Toll-like receptor 9 Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MWD3 A0A8I3N971 A0A8I3N9M7 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWT3 A0A8I3Q7B4 A0A8I3QFN1 A0A8I3RTN7 A0A8I3S0I1 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0 Q5I2M8	FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 GAB1 GAB2 GRB2 IRS1 IRS2 KGF KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9
CD22 mediated BCR regulation	B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD79a molecule CD79b molecule Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3MIL9 A0A8I3MUW4 A0A8I3NVL7 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P501 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDA6 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWC6 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P0CAN6	CD79A CD79B IGHM LYN MAG PTPN6
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 KL PLCG1
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A8I3NI15 A0A8I3NVW9 A0A8I3PAR4 A0A8I3RQ77 A0A8I3S0I1 P33712	IGF1 IGF1R IGF2 IGFIA IRS1 IRS2 IRS4
Cargo concentration in the ER	Alpha 1 antitrypsin Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein Prolactin regulatory element-binding protein Protein cornichon homolog 2 Protein transport protein SEC23 SEC22 homolog B, vesicle trafficking protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Syntaxin 5 Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Vesicular integral-membrane protein VIP36 cathepsin X	A0A8I3MAV2 A0A8I3MLH1 A0A8I3MT80 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3N2I9 A0A8I3N5W4 A0A8I3N796 A0A8I3N9V0 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NYM5 A0A8I3NZH7 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PEN5 A0A8I3PQR9 A0A8I3PTW0 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RU45 A0A8I3RWZ7 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 P49256	AREG CD59 CNIH1 CNIH2 CNIH3 CTSC CTSZ F5 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 MIA2 PREB SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 TGFA TMED10 TMED2
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Corticoliberin Corticotropin releasing hormone receptor 2 Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Sushi domain-containing protein Tuberoinfundibular peptide of 39 residues Uncharacterized protein Uncharacterized protein Urocortin	A0A8I3MZB5 A0A8I3P6W0 A0A8I3P7R9 A0A8I3PCJ2 A0A8I3PCP1 A0A8I3PHA9 A0A8I3PPK6 A0A8I3PPW2 A0A8I3RQ73 A0A8I3RSJ3 A0A8I3RVU2 A0A8I3RXL4 P52211 P52212 Q2Q423 Q9TU31	ADGRE1 ADGRE3 ADGRE5 CD55 CRH CRHBP CRHR1 CRHR2 LOC484897 PTH PTH1 PTH1R PTH2 PTH2R PTHLH PTHR1 UCN UCN3
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Multifunctional fusion protein Ras-related protein Rab-3 Regulating synaptic membrane exocytosis 1 Synaptotagmin Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	A0A8I3ME77 A0A8I3MLF8 A0A8I3MQ89 A0A8I3N2E5 A0A8I3N5Z9 A0A8I3NNW3 A0A8I3P737 A0A8I3PDP4 A0A8I3PNE3 A0A8I3Q823 A0A8I3S6J8 A0PA85 Q4PRC2	CPLX1 DNAJC5 GAD1 GAD2 GAD65 GAD67 LOC607182 RAB3A RIMS1 SLC32A1 SNAP25 STX1A STXBP1 SYT1 VAMP2
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-lysine N-methyltransferase Cyclic nucleotide gated channel subunit beta 1 EF-hand domain-containing protein G protein-coupled receptor kinase G protein-coupled receptor kinase G protein-coupled receptor kinase Glycylpeptide N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein subunit beta-5 Guanylate cyclase activator 1C Guanylate cyclase Guanylate cyclase Guanylyl cyclase-activating protein 1 Methionine aminopeptidase 2 Methionine aminopeptidase Phosphodiesterase Recoverin Regulator of G protein signaling 9 binding protein Regulator of G-protein signaling 9 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Serine/threonine-protein phosphatase with EF-hands cGMP-gated cation channel alpha-1	A0A8I3MKZ0 A0A8I3MLZ0 A0A8I3MQ38 A0A8I3MR23 A0A8I3MSQ7 A0A8I3NB80 A0A8I3NDY5 A0A8I3NJ95 A0A8I3NUA6 A0A8I3P9Q1 A0A8I3PF51 A0A8I3PM46 A0A8I3PRB5 A0A8I3PV05 A0A8I3PV39 A0A8I3PWQ2 A0A8I3Q053 A0A8I3Q0S6 A0A8I3Q144 A0A8I3QE57 A0A8I3S5I9 A0A8I3S6V0 P33726 P54827 Q28263 Q28300 Q8MIH6	CALM2 CAMKMT CNGA1 CNGB1 GNAT1 GNB5 GRK1 GRK4 GRK7 GUCA1A GUCA1C GUCY2D GUCY2F METAP1 METAP2 NMT1 NMT2 PDBS PDE6A PDE6B PDE6G PDEA PDEB PDEG PPEF1 RCV1 RCVRN RGS9 RGS9BP RHO SAG
FRS-mediated FGFR2 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NM39 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 FRS3 GRB2 HRAS KGF KRAS NRAS PTPN11 SOS1
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain containing linker protein 3 Caspase 8 Caspase 9 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TANK binding kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tax1 binding protein 1 Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MAP5 A0A8I3MDM0 A0A8I3MJ82 A0A8I3MKR0 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3NEJ2 A0A8I3NFB9 A0A8I3NK16 A0A8I3NLZ9 A0A8I3NP69 A0A8I3NS04 A0A8I3P2P4 A0A8I3P499 A0A8I3PLX1 A0A8I3PRU0 A0A8I3PS24 A0A8I3PT83 A0A8I3PW29 A0A8I3PWL6 A0A8I3PZS6 A0A8I3Q155 A0A8I3Q3L1 A0A8I3QYD0 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3RZI9 A0A8I3S2L7 A0A8I3S5W5 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 P63050 Q38IV1 Q38JA9	BIRC2 BIRC3 BIRC4 CASP8 CASP9 CHUK CLIP3 CYLD IKBKB IKBKE IKBKG IRF9 MADD MIB2 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4 XIAP
Costimulation by the CD28 family	B and T lymphocyte associated Growth factor receptor bound protein 2 Ig-like domain-containing protein Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 TNF receptor superfamily member 14 Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3P405 A0A8I3P519 A0A8I3P6Z0 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWC6 A0A8I3Q857 A0A8I3S3N2 Q7YR73	AILIM BTLA GRB2 ICOS ICOSLG LOC100856339 PIK3CA PIK3R1 PIK3R2 PTPN11 PTPN6 TNFRSF14
TNFs bind their physiological receptors	CD27 molecule CD70 molecule EDAR associated via death domain Ectodysplasin A receptor Ectodysplasin A LIGHT Lymphotoxin-alpha Migration and invasion inhibitory protein TNF family profile domain-containing protein TNF receptor superfamily member 14 TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 1B TNF receptor superfamily member 6b TNF receptor superfamily member 9 TNF superfamily member 13 TNF superfamily member 13b TNF superfamily member 18 TNF superfamily member 4 TNF superfamily member 8 TNFR-Cys domain-containing protein Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 11B Uncharacterized protein Uncharacterized protein	A0A0U5JAK9 A0A8I3MEA7 A0A8I3MKG7 A0A8I3MM10 A0A8I3MPQ0 A0A8I3N568 A0A8I3NB07 A0A8I3NFC1 A0A8I3NGJ3 A0A8I3NJU2 A0A8I3NZX5 A0A8I3P405 A0A8I3PKB9 A0A8I3PLK9 A0A8I3PMM9 A0A8I3Q3L1 A0A8I3Q7M4 A0A8I3QDG0 A0A8I3S9F2 E2R8I1 E2RP79 J9JHM5 J9P753 Q58P77 Q5WR07	CD27 CD70 EDA EDAR EDARADD LTA MIIP TNFB TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF4 TNFRSF6B TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNLG1D TNLG2A TNLG2B TNLG3A TNLG7A
Activation of the phototransduction cascade	Cyclic nucleotide gated channel subunit beta 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Phosphodiesterase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta cGMP-gated cation channel alpha-1	A0A8I3MLZ0 A0A8I3MQ38 A0A8I3NB80 A0A8I3QE57 P33726 P54827 P62872 P63210 Q28263 Q28300	CNGA1 CNGB1 GNAT1 GNB1 GNGT1 PDBS PDE6A PDE6B PDE6G PDEA PDEB PDEG RHO
MAP2K and MAPK activation	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of Ras 1 Connector enhancer of kinase suppressor of Ras 2 Dual specificity mitogen-activated protein kinase kinase 2 Fibronectin GTPase HRas GTPase NRas Integrin beta Integrin subunit alpha 2b Interleukin 17 receptor D Kinase suppressor of ras 1 Kinase suppressor of ras 2 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Mitogen-activated protein kinase Mitogen-activated protein kinase Phosphatidylethanolamine-binding protein 1 Phosphatidylethanolamine-binding protein 1 RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR3 Talin 1 Tyrosine-protein kinase Tyrosine-protein kinase Vinculin WD repeat domain-containing protein 83 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase small monomeric GTPase small monomeric GTPase small monomeric GTPase von Willebrand factor von Willebrand factor	A0A8I3N6K0 A0A8I3N737 A0A8I3N7S1 A0A8I3NR25 A0A8I3NUL4 A0A8I3P1J7 A0A8I3P2I8 A0A8I3P4Z0 A0A8I3PDX9 A0A8I3PED8 A0A8I3PMU9 A0A8I3PP92 A0A8I3PSP7 A0A8I3PTA1 A0A8I3PZA0 A0A8I3PZB5 A0A8I3PZP0 A0A8I3Q1I3 A0A8I3Q3R4 A0A8I3Q981 A0A8I3RQD0 A0A8I3RUF3 A0A8I3RVR5 A0A8I3RXW5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S756 A0A8I3SAZ0 A0A8I3SBF9 A0A8I3SCK0 A0A8I3SCX1 Q1HG70 Q28295 Q3YIX4	APBB1IP ARAF ARRB1 ARRB2 BRAF CNKSR1 CNKSR2 CSK F8VWF FN1 HRAS IL17RD ITGA2B ITGB3 KRAS KSR1 KSR2 LAMTOR2 LAMTOR3 MAP2K2 MAPK1 MAPK3 MARK3 MEK2 NRAS PBP PEBP1 RAF1 RAP1A RAP1B SRC TLN1 VCL VWF WDR83
Extracellular matrix organization	Fibronectin	A0A8I3PED8	FN1
The canonical retinoid cycle in rods (twilight vision)	ATP binding cassette subfamily A member 4 Cytochrome P450 family 4 subfamily V member 2 Cytosolic fatty-acid binding proteins domain-containing protein Dehydrogenase/reductase 9 Hydroxysteroid 17-beta dehydrogenase 6 Lecithin retinol acyltransferase Myosin VIIA NADP-retinol dehydrogenase Plasma retinol-binding protein Receptor for retinol uptake STRA6 Retinaldehyde binding protein 1 Retinoid isomerohydrolase Retinol binding protein 3 Retinol dehydrogenase 12 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Rhodopsin Short chain dehydrogenase/reductase family 9C member 7 Transthyretin	A0A8I3MJB9 A0A8I3MRK7 A0A8I3MTG2 A0A8I3N0K5 A0A8I3N0Y3 A0A8I3N2V4 A0A8I3N8N5 A0A8I3NEZ4 A0A8I3NFK0 A0A8I3NXV6 A0A8I3P9M8 A0A8I3PAT8 A0A8I3Q0S8 A0A8I3Q3P2 A0A8I3QE57 A0A8I3QHU9 A0A8I3RVK1 A0A8I3RWP2 A0A8I3S143	ABCA4 CYP4V2 DHRS9 HSD17B6 LRAT MYO7A RBP1 RBP3 RBP4 RDH10 RDH12 RDH16 RDH5 RHO RLBP1 RPE65 SDR9C7 STRA6 TTR

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