GlyCosmos Portal

Sus scrofa (pig)

Summary

Taxonomy ID: 9823
PubChem Taxonomy: 9823

Genes (1563) Glycans (767) Glycoproteins (761) Lectins (33) Pathways (361)

Displaying entries **276 - 300** of **361** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Melanin biosynthesis	5,6-dihydroxyindole-2-carboxylic acid oxidase L-dopachrome tautomerase OCA2 melanosomal transmembrane protein Solute carrier family 45 member 2 Tyrosinase	A0A8W4FBC9 F1SP14 F6Q7U8 Q4R1H1 Q4R1H3	DCT OCA2 SLC45A2 TYR TYRP1 TYRP2
Lysosome Vesicle Biogenesis	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit beta AP complex subunit sigma AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-4 complex subunit mu-1 Adaptor related protein complex 4 subunit epsilon 1 Amyloid-beta A4 protein Amyloid-beta precursor protein Beta-arrestin-1 Charged multivesicular body protein 2a Clathrin heavy chain Clathrin light chain Clathrin light chain Clavesin-1 Deoxyribonuclease-2-alpha Deoxyribonuclease-2-alpha Hepatocyte growth factor-regulated tyrosine kinase substrate Mannose-6-phosphate receptor, cation dependent N-acetylglucosamine-6-sulfatase Thioredoxin domain containing 5 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 8 cathepsin X dynamin GTPase	A0A286ZND1 A0A286ZTE6 A0A287A524 A0A287A638 A0A287A682 A0A287A8E1 A0A287ARZ1 A0A287B610 A0A287B8X7 A0A287BFZ5 A0A5G2Q9Y0 A0A5G2QSL5 A0A5G2R276 A0A8W4F8A7 A0A8W4FA01 A0A8W4FAA6 A5GFX7 F1RFI2 F1RT89 F1RYM9 F1S3C7 F1SBR2 F1SDY3 F1SLX0 F1SS42 I3LE99 I3LSS2 O62855 P79307	A4 AD1 AP1B1 AP1G1 AP1G2 AP1M1 AP1M2 AP1S1 AP1S3 AP4B1 AP4E1 AP4M1 APP ARF1 ARRB1 CHMP2A CLTA CLTB CLTC CLVS1 CTSZ DNASE2 DNASE2A DNL2 DNM2 GNS HGS M6PR TXNDC5 VAMP2 VAMP8
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Amphiregulin Betacellulin Epiregulin Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha	A0A287A231 A0A287A6I2 A0A287AZM9 A0A5G2QBP1 F1SDV6 F1SLD3 Q01580 Q9BDH4	AREG BTC DTR EGF EGFR EREG HBEGF HEGFL PLCG1 TGFA
Surfactant metabolism	ATP binding cassette subfamily A member 3 Adenosine receptor A2 Adenosine receptor A2 Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Coiled-coil domain containing 59 Cytoskeleton associated protein 4 Deleted in malignant brain tumors 1 protein GATA binding protein 6 LIM and cysteine rich domains 1 LIM and cysteine-rich domains protein 1 Napsin A aspartic peptidase P2Y purinoceptor 2 Palmitoyltransferase Pepsin A Pro-cathepsin H Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Pulmonary surfactant-associated protein D Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Transcription termination factor 1 adenosine deaminase	A0A287A5E9 A0A287AH87 A0A287AN35 A0A287ANT3 A0A287AYY3 A0A287BDN3 A0A287BPZ1 A0A480WFR8 A0A5G2Q8A7 A0A8W4FD62 A0A8W4FEE8 A7MAK5 F1RLS0 F1S0U5 F1S5A6 F1SBC0 F1SPP8 I3LFJ1 O46427 P00791 P18871 Q3MSM1 Q5PXT2 Q5YA25 Q9N1X4	A2AR ABCA3 ADA2 ADGRF5 ADORA2A ADORA2B ADRA2A ADRA2C CCDC59 CKAP4 CTSH GATA6 LMCD1 NAPSA P2RY2 PGA SFTPB SFTPC SFTPD SLC34A1 SLC34A2 SP-C TTF1 ZDHHC2
O-linked glycosylation of mucins	Alpha-1,4-N-acetylglucosaminyltransferase Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase C1GALT1-specific chaperone 1 Glucosaminyl (N-acetyl) transferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Mucin 13, cell surface associated Mucin 15, cell surface associated Mucin 2, oligomeric mucus/gel-forming Mucin 20, cell surface associated Mucin 4, cell surface associated Mucin 5AC, oligomeric mucus/gel-forming Mucin 5B, oligomeric mucus/gel-forming Mucin 6, oligomeric mucus/gel-forming Mucin-1 Polypeptide N-acetylgalactosaminyltransferase like 5 Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase SEA domain-containing protein Sulfotransferase UDP-GlcNAc	A0A1S6M251 A0A286ZLM1 A0A286ZNW2 A0A287A1R2 A0A287A6N0 A0A287A7J0 A0A287AIU3 A0A287ASH2 A0A287B5M2 A0A287B5N4 A0A287BKI9 A0A5G2QU42 A0A5G2R0V1 A0A5G2R1K9 A0A5G2R9D7 A0A8W4FAW4 A0A8W4FBP7 A0A8W4FES6 A0A8W4FM62 A5GFW8 F1RGR9 F1RIZ9 F1RJJ7 F1RQC2 F1RUC2 F1S070 F1S2M2 F1S3D0 F1S3Y5 F1S4B7 F1S6W6 F1SAI6 F1SFZ5 F1SIN0 F1SIW5 F1SQ58 F1SSE9 F1SSN3 F6Q8N2 I3LAJ3 I3LCH7 I3LFY2 I3LK83 I3LSM2 Q864U8	A4GNT B3GNT2 B3GNT4 B3GNT5 B3GNT6 B3GNT7 B3GNT8 B3GNT9 B3GNTL1 B4GALT5 B4GALT6 C1GALT1 C1GALT1C1 CHST4 GALNT1 GALNT10 GALNT11 GALNT12 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL5 GCNT1 GCNT3 GCNT4 GCNT7 MUC1 MUC13 MUC15 MUC2 MUC20 MUC4 MUC5AC MUC5B MUC6
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glutathione S-transferase omega-1 NADH-cytochrome b5 reductase Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 23 member 1	A0A5G2QPB6 I3LCS3 O62787 P00172 P20303 Q9N1F5	CYB5 CYB5A CYB5R3 GLUT1 GLUT3 GSTO1 SLC23A1 SLC2A1 SLC2A3
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Cathepsin L	F1S4J6 Q9GLE3	CTSK CTSL
Aflatoxin activation and detoxification	Aflatoxin B1 aldehyde reductase member 4 Aminoacylase-1 Cytochrome P450 1A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 Dipeptidase 1 Dipeptidase Dipeptidase Gamma-glutamyltransferase 6 Glutathione hydrolase Glutathione hydrolase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 Microsomal glutathione S-transferase 3	A0A0K1TQQ0 A0A287B7I8 A0A5G2R0Q5 A0A5K1UGB8 F1S4Y1 F1SJ26 F1SUP1 I3L719 I3LA57 I3LEX8 I3LFR7 P22412 P37111 P79382 Q2EN77 Q8SQ68	ACY1 AKR7A2 CYP1A2 CYP2A19 CYP3A22 CYP3A227 CYP3A29 DPEP1 DPEP2 GGT1 GGT6 GGT7 GST12 MGST1 MGST2 MGST3 RDP
NTRK2 activates RAC1	Brain-derived neurotrophic factor Dedicator of cytokinesis 3 Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase Fyn	A0A287AKJ4 A0A8W4FI56 A1Y2K1 P14082	BDNF DOCK3 FYN RAC1
The canonical retinoid cycle in rods (twilight vision)	ATP binding cassette subfamily A member 4 Cytochrome P450 family 4 subfamily V member 2 Lecithin retinol acyltransferase NADP-retinol dehydrogenase Receptor for retinol uptake STRA6 Retinol binding protein 1 Retinol binding protein 3 Retinol dehydrogenase 11 Retinol dehydrogenase 12 Retinol dehydrogenase 5 Retinol-binding protein Rhodopsin Short chain dehydrogenase/reductase family 9C member 7 Transthyretin Transthyretin Uncharacterized protein	A0A286ZUS8 A0A287B1J6 A0A287B476 A0A5G2QIE9 A0A5G2QTV7 F1RYR6 F1S539 F1SA23 F1SA24 F1SC80 F1SEL7 F1SIE2 F1SL80 F1SPK7 O18766 P50390	ABCA4 CYP4V2 LOC100626199 LRAT RBP1 RBP3 RBP4 RDH10 RDH11 RDH12 RDH5 RHO RHO1 SDR9C7 STRA6 TTR
Ion transport by P-type ATPases	ATPase 13A1 ATPase Na+/K+ transporting subunit alpha 3 ATPase cation transporting 13A2 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin 3 Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase FXYD domain-containing ion transport regulator P-type Cu(+) transporter PDZ domain-containing protein 11 Phospholemman Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Potassium-transporting ATPase subunit beta Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A287A226 A0A287AFK3 A0A287AL21 A0A287APC7 A0A287B705 A0A287B7D1 A0A287B7S6 A0A287BAN5 A0A287BCC5 A0A5G2Q8V3 A0A5G2QCQ9 A0A5G2QQF7 A0A5G2QSB0 A0A5G2QWK6 A0A5G2RAC3 A0A5G2RDL8 A0A5K1U0J0 A0A5K1VCX5 A0A8W4FK37 A0A8W4FN13 A0A8X9AEX2 D2WKD8 F1RL74 F1RM59 F1RQ73 F1S340 F1S3S6 F1SDH8 F1SFG8 F1SM35 F1SNN7 F1SQH3 F1ST41 F1SUR9 I3LIK9 I3LMB3 I3LN55 I3LUR3 K7GQ24 O77696 P05027 P11607 P18434 P61013 Q6QA76 Q95266	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A2 ATP1A3 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP7A ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B3 ATP8B4 ATP9A ATP9B CALM3 CAMK2A CAMK2B CAMK2D CAMK2G FXYD1 FXYD6 PDZD11 PDZK11 PLM PLN SRI
Gastrin-CREB signalling pathway via PKC and MAPK	Mitogen-activated protein kinase Mitogen-activated protein kinase Mitogen-activated protein kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A287A3K5 A0A287BHE2 A0A480NH74 A0A5G2R6J0 A0A5G2RG05 M3VH78	MAPK1 MAPK3 MAPK7 RPS6KA1 RPS6KA2 RPS6KA3
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1 Histone deacetylase 6	A0A287BPX4 I3L925	ATAT1 HDAC6 MEC17
SHC-mediated cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A5G2QLX0 A0A5G2R7G2 A0A5K1V5Y3 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1SET9 F1SMG2 I3LCQ9 K7GQJ1 Q2MJK3 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 GRB2 HRAS KL KRAS NRAS SHC1 SOS1
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Amphiregulin Betacellulin Brain-derived neurotrophic factor CD80 molecule CD86 molecule Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 4 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Neurotrophin-3 Neurotrophin-4 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphoinositide-3-kinase adaptor protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proline rich 5 Proto-oncogene vav RPTOR independent companion of MTOR complex 2 Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein kinase mTOR Striatin T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Target of rapamycin complex subunit LST8 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A140TAK4 A0A286ZJM1 A0A286ZQX2 A0A286ZSM8 A0A286ZV67 A0A287A231 A0A287A6I2 A0A287A8R7 A0A287AAE4 A0A287ADF0 A0A287AFX3 A0A287AXR0 A0A287AYB4 A0A287AZM9 A0A287B3V5 A0A287B510 A0A287B5E0 A0A287B630 A0A287B726 A0A287B929 A0A287BCW9 A0A287BG34 A0A287BGK8 A0A287BK67 A0A480ECT1 A0A480J4F4 A0A480LMF4 A0A5G2QBP1 A0A5G2QL24 A0A5G2QNL8 A0A5G2QUY7 A0A5G2R1H6 A0A5G2R1K1 A0A5G2R7G2 A0A5G2RJR4 A0A5K1UB41 A0A5K1UPW2 A0A8W4FI56 A0A8W4FMH5 A0A8X9AEI7 A1Y2K1 A7XUJ6 B6E241 F1RFA8 F1RHR8 F1RIN3 F1RL75 F1RM38 F1RSR6 F1RWM5 F1RY78 F1RY80 F1RZU1 F1S3B8 F1S4P0 F1S916 F1SB93 F1SET9 F1SKR9 F1SLD3 F1SMG2 F1SRR6 F1SSQ9 F1SV94 F6Q7E6 I3L560 I3LEK8 I3LKR6 I3LLF1 I3LR27 K7GMT0 K7GMU1 K7GPR7 K7GQJ1 P14082 Q01580 Q29040 Q2QLE0 Q95L12 Q9BDH4 Q9BE99	AREG BDNF BTC CD28 CD80 CD80/B7-1 CD86 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HEGFL HGF IL1RL1 IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MET MLST8 MTOR MYD88 NR3A1 NRG1 NRG2 NRG3 NTF3 NTF4 NTRK3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRR5 PTPN11 RAC1 RAC2 RHOG RICTOR SRC STRN TGFA TRAF6 VAV1
Negative regulation of the PI3K/AKT network	Phosphatase and tensin homolog	F2Z5H1	PTEN
Activated NTRK2 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Brain-derived neurotrophic factor Neurotrophin-4	F1RIN3 F1SDV6 P14082	BDNF NTF4 PLCG1
SHC-mediated cascade:FGFR4	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A5G2QLX0 A0A5G2QUY7 A0A5G2R7G2 A0A5K1V5Y3 B6E241 F1RM38 F1RY80 F1S3B8 F1SET9 I3L560 I3LCQ9 I3LR27 Q2MJK3 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GRB2 HRAS KLB KRAS NRAS SHC1 SOS1
Toll Like Receptor 10 (TLR10) Cascade	Toll like receptor 10	I3LPE4	TLR10
EGFR Transactivation by Gastrin	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1 small monomeric GTPase	A0A286ZUQ0 A0A5G2QBP1 A0A5G2QLX0 B6E241 F1RV14 F1SV58 I3LCQ9 Q01580 Q2MJK3	DTR EGFR GRB2 HBEGF HEGFL HRAS KRAS MMP3 NRAS PRKCA SOS1
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Artemin Cell division cycle 25C Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 GDNF family receptor alpha 1 GDNF family receptor alpha 4 GDNF family receptor alpha-2 GRB2 associated binding protein 1 GRB2 associated binding protein 2 Glial cell derived neurotrophic factor Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Growth factor receptor-bound protein 10 Insulin receptor substrate 2 Mitogen-activated protein kinase Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Protein kinase C Proto-oncogene tyrosine-protein kinase receptor Ret RAP1 GTPase activating protein SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZUQ0 A0A287ADY7 A0A287AY39 A0A287B5X0 A0A287B630 A0A287B726 A0A287B731 A0A287BDL2 A0A287BEY5 A0A480LMF4 A0A5G2QY14 A0A5K1UB41 A0A5K1UPW2 A0A5K1V5Y3 A0A8W4F937 A0A8W4FLI0 A0A8X9AEI7 A5GFP8 B5KFD7 B6E241 F1RG22 F1RH78 F1RMC2 F1RMZ6 F1RV14 F1RX94 F1S916 F1SBT4 F1SDV6 F1SKR9 F1SNV8 I3L7P2 K7GMT0 K7GPR7 M3VH78	ARTN CDC25C DOK1 DOK2 DOK4 DOK5 DOK6 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 GRB7 Grb10 IRS2 MAPK7 NRTN PDLIM7 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PLCG1 PRKCA PSPN PTPN11 RAP1GAP RET SHC1 SHC3 SOS1 SRC
Regulation of Complement cascade	C5a anaphylatoxin chemotactic receptor 1 CD55 molecule (Cromer blood group) CD59 glycoprotein CD81 molecule Carboxypeptidase B2 Carboxypeptidase N catalytic chain Carboxypeptidase N subunit 2 Clusterin Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C4A (Rodgers blood group) Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor H Complement factor I Ig lambda chain C region Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Plasma protease C1 inhibitor Prothrombin Sushi domain-containing protein Sushi domain-containing protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A075B7I6 A0A0A0MY58 A0A286ZIM1 A0A286ZJL9 A0A286ZKR7 A0A286ZLN6 A0A286ZMU4 A0A286ZP42 A0A286ZQH2 A0A286ZSJ7 A0A286ZSX6 A0A286ZTI5 A0A286ZU07 A0A286ZUL8 A0A287A3T6 A0A287A7S8 A0A287AA42 A0A287ADE7 A0A287AE51 A0A287AFQ4 A0A287AIM8 A0A287AKW2 A0A287ALJ6 A0A287AM45 A0A287AM58 A0A287ANU5 A0A287AP28 A0A287APG4 A0A287AQ20 A0A287AT36 A0A287AU93 A0A287AUR4 A0A287AWH3 A0A287AWQ8 A0A287AYC4 A0A287B1Y4 A0A287B5G0 A0A287B6Q2 A0A287BAB3 A0A287BD18 A0A287BDV3 A0A287BH28 A0A287BHK5 A0A287BLF6 A0A287BLH9 A0A287BMT4 A0A287BNF7 A0A287BNX9 A0A287BRE1 A0A480RJC3 A0A5G2NLY0 A0A5G2Q7F8 A0A5G2Q7Q6 A0A5G2QCL1 A0A5G2QHE8 A0A5G2QNN2 A0A5G2QXT5 A0A5G2R8T9 A0A5G2R9V1 A0A5S8KLN1 A0A8W4F6L3 A0A8W4F7N5 A0A8W4F807 A0A8W4F8A6 A0A8W4F8U6 A0A8W4F9I3 A0A8W4FA34 A0A8W4FAN5 A0A8W4FC14 A0A8W4FC15 A0A8W4FC67 A0A8W4FDG3 A0A8W4FDT9 A0A8W4FEK6 A0A8W4FEL9 A0A8W4FGI9 A0A8W4FGK7 A0A8W4FHQ3 A0A8W4FHY5 A0A8W4FI53 A0A8W4FJA1 A0A8W4FJL3 A0A8W4FL59 A0A8W4FLJ3 A0A8W4FMG3 A0A8W4FMI6 A0A8W4FN37 A0A8W4FNE8 A0A8W4FQ38 A0A8W4FQC5 A0A8W4FRI5 F1RK01 F1RL06 F1RQW7 F1S788 F1S8V7 F1S9H7 F1SIB1 F1SJW8 F1SMJ1 F1STC2 F1STC3 F1STC5 I3L6U3 I3LBK0 I3LF89 I3LUE7 K7GLM8 K7GPT9 O62680 P01846 P48819 Q29549	C1QA C1QB C1QC C1R C1S C2 C3 C4A C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD55 CD59 CD81 CFB CFH CFI CLU CPB2 CPN1 CPN2 F2 IGKV5-2 LOC100125542 LOC100523213 SERPING1 VTN
RHOC GTPase cycle	A-kinase anchor protein 13 ATP binding cassette subfamily D member 3 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin, actin binding protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin Citron Rho-interacting kinase Coiled-coil domain containing 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 Flotillin-1 Flotillin Formin like 2 Formin like 3 Guanine nucleotide exchange factor DBS isoform X2 IQ motif containing GTPase activating protein 3 Junction plakoglobin Junction plakoglobin Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence Macoilin Melanoma cell adhesion molecule Myosin IXB Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Rac GTPase activating protein 1 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 2 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rhotekin Stomatin Tight junction protein 2 Transferrin receptor protein 1 Transferrin receptor protein 1 Transforming protein RhoA VAMP associated protein B and C Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase protein kinase C protein kinase C protein kinase C	A0A0D5BWD2 A0A286ZJQ9 A0A286ZLF6 A0A286ZUE0 A0A286ZZ97 A0A287A7V4 A0A287AAT1 A0A287AIC4 A0A287AJS0 A0A287ALN0 A0A287APG0 A0A287AQA7 A0A287AQX9 A0A287AV56 A0A287AYN9 A0A287AZG0 A0A287B186 A0A287B310 A0A287B8N4 A0A287BEC7 A0A287BF14 A0A287BT99 A0A2C9F3E9 A0A480QRR0 A0A481A732 A0A481BTZ2 A0A5G2QA45 A0A5G2QIS7 A0A5G2QRI9 A0A5G2QXS5 A0A5G2R1A0 A0A5G2R5Z3 A0A5G2REY5 A0A5S6GXI4 A0A8W4FBH6 A0A8W4FG77 A0A8W4FKM4 A0A8W4FMS3 A0A8W4FNA4 A5GFS8 E7EI20 F1RJ64 F1RM07 F1RQ74 F1RSQ1 F1S2Z5 F1SAW7 F1SCI4 F1SEU3 F1SH88 F1SIM2 F1SKH7 F1SKR9 F1SMS8 F1SUT6 I3LBU6 I3LD06 I3LDR4 I3LI20 I3LKY7 I3LQ81 I3LQV1 I3LVS7 M3TYT0 M3VH35 Q2TLZ2 Q767L6 Q8HZV3 Q8WNW3	ABCD3 ABR ACBD5 AKAP13 ANLN ARHGAP1 ARHGAP18 ARHGAP21 ARHGAP26 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF5 BCR C1QBP CAV1 CAVIN1 CIT DAAM1 DEPDC1B DIAPH1 DIAPH3 DLC1 FLOT1 FLOT2 FMNL2 FMNL3 IQGAP3 JUP Jup LBR LMAN1 MACO1 MCAM MCF2 MCF2L MYO9B OPHN1 PIK3R1 PKN1 PKN2 PKN3 PREX1 RACGAP1 RHOA RHOC ROCK1 ROCK2 RTKN SLK STOM TFRC TJP2 TMEM57 VAMP3 VANGL1 VAPB VAV2
RND2 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Bridge-like lipid transfer protein family member 3B Caveolin Cytoskeleton associated protein 4 DEP domain containing 1B Desmoglein 1 Desmoglein-1 Discs large MAGUK scaffold protein 5 Dystonin Family with sequence similarity 83 member B Fibroblast growth factor receptor substrate 3 Formin binding protein 1 Golgin A3 Kinase D interacting substrate 220 Kinectin 1 Leucine rich repeat containing 1 Mucin 13, cell surface associated Nischarin Nuclear migration protein nudC Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin 4 Plexin D1 RNA binding motif protein 39 Rho GTPase activating protein 1 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho family GTPase 2 Scribble planar cell polarity protein Thioredoxin like 1 Transferrin receptor protein 1 Transferrin receptor protein 1 Tyrosine-protein phosphatase non-receptor type 13 UBX domain protein 11 Uncharacterized protein Vang-like protein Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A286ZJQ9 A0A286ZPP2 A0A287ABR1 A0A287AH84 A0A287AIV8 A0A287AZG0 A0A287B8R2 A0A287BAQ0 A0A287BBJ7 A0A287BCT3 A0A287BF82 A0A287BKB6 A0A287BQA2 A0A480JZF5 A0A5G2QA45 A0A5G2QWP0 A0A5G2RKR1 A0A5S6GXI4 A0A8W4FAC1 A0A8W4FQG7 F1RI72 F1RJY3 F1RM07 F1RUW8 F1RZV9 F1RZW2 F1S1X9 F1S916 F1SAW7 F1SKR9 F1SPP8 F1SQ58 F1SSN5 F1SUT8 I3LA65 I3LD06 I3LM60 I3LMD8 I3LQJ8 Q3BDI7 Q8HZV3	ALDH3A2 ARHGAP1 ARHGAP35 ARHGAP5 BLTP3B CAV1 CKAP4 DEPDC1B DLG5 DSG1 DST EPHA2 FAM83B FNBP1 FRS3 GOLGA3 KCTD13 KIDINS220 KTN1 LOC100516390 LRRC1 MUC13 NISCH NUDC PIK3R1 PIK3R2 PKP4 PLXND1 PTPN13 RBM39 RND2 SCRIB TFRC TNFAIP1 TXNL1 UBXN11 VANGL1 VANGL2 WDR6
TGF-beta receptor signaling activates SMADs	E2 NEDD8-conjugating enzyme E3 ubiquitin-protein ligase CBL Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog NEDD8 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta receptor 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta Zinc finger FYVE domain-containing protein furin peptidylprolyl isomerase	A0A286ZQE1 A0A286ZV08 A0A286ZWQ1 A0A287AE63 A0A287AZ66 A0A287BE69 A0A287BIH5 A0A287BIQ9 A0A287BLR9 A0A287BNE4 A0A287BPI7 A0A5G2R7K7 A0A5G2RC56 A0A5K1V6L8 A0A8W4FF41 A9X6R3 F1RMJ1 F1RRJ9 F1RW86 K7GQ83 K7GSJ9 P07200 P15203 P84024 Q2VTP6 Q9GKQ9	CBL FKBP1A FURIN ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP3 LTBP4 MADH3 MADH4 NEDD8 SMAD2 SMAD3 SMAD4 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBE2M ZFYVE9

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