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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Yersinia pestis | PsaA/B (pH-6 antigen) | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | F1C | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Escherichia coli | F1C | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Escherichia coli | F1C | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Cytomegalovirus | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Cytomegalovirus | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Escherichia coli | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Unknown | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Unknown | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Unknown | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Helicobacter pylori | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9169796 | |
| Escherichia coli | S-fimbriae | alpha-sialyl-beta-2,3-galactose-containing glycolipids and glycoproteins | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 2883653 | |
| Escherichia coli | S-fimbriae | unnamed ligand | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 11454740 | |
| Escherichia coli | SfaS | unnamed ligand | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 10341176 | |
| Influenza virus | Unknown | Sia2-3Gal-containing receptors | Glycoconjugates | NeuAc(a2-3)Gal | Binding | 9882316 | |
| Influenza virus | Hemagglutinin | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
| Histoplasma capsulatum | Lectin-like component | Galactosylated surface molecules (mainly β-anomer) | Glycoconjugates | Murine macrophages | Binding | 19547878 | |
| Influenza virus | Hemagglutinin H1(1934) | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
| Paramyxovirus | Hemagglutinin H1(1934) | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
| Escherichia coli | Type 1-fimbriae | β-D-glycosides | Glycoconjugates | Patient with urinary tract infection | Binding | 6138149 | |
| Plasmodium falciparum | Unknown | Neuraminidase-insensitive, trypsin sensitive carbohydrate ligand | Glycoconjugates | Molecules on the erythrocyte membrane (other than glycophorins A and B) | Binding | 3308959 | |
| Listeria monocytogenes | Unknown | α-GalCer/CD1d tetramers | Glycoconjugates | V[alpha]14+ NK1.1- T cells in infected liver of mice | Binding | 16988270 | |
| Rotavirus | Virus Spike Protein VP4 (mapped between aminoacids 93 and 208 of its trypsin cleavage fragment VP8) | Sialic acid-containing cell compounds | Glycoconjugates | Binding | 9261399 | ||
| Influenza virus | SNA lectins | Minor NeuAcα6-containing molecules | Glycoconjugates | Human leukocytes | Binding | 11030743 |
