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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | S-fimbriae | alpha-sialyl-beta-2,3-galactose-containing glycolipids and glycoproteins | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 2883653 | |
| Pseudomonas aeruginosa | LecB | alpha-methyl-fucoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Escherichia coli | PapG | alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose | Disaccharides | Uroepithelial cells | Gal(a1-4)Gal | Binding | 2886993 |
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Escherichia coli | FimH | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Streptococcus pneumoniae | Unknown | Trisaccharides | Oligosaccharides | GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 | |
| Neisseria meningitidis | Type 4-pili | Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans | Glycoproteins | Bovine | Binding | 16177210 | |
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Haemophilus influenzae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Neisseria meningitidis | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 | |
| Norovirus | Unknown | Terminal N-Acetylgalactosamine residue in an alpha linkage | Saccharides | Oyster digestive tissues | Binding | 16707048 | |
| Escherichia coli | FimH | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | P-pili | Surfactant-like particles (SLP) | Non-glycosylated Lipids | Human colonocytes and enterocytes | Binding | 10531281 | |
| Escherichia coli | PapD-PapG (class I) | Surfactant-like particles (SLP) | Non-glycosylated Lipids | Human colonocytes and enterocytes | Binding | 10531281 | |
| Pseudomonas aeruginosa | Type 4-pili | Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins) | Glycoconjugates | Human epithelial cells | Binding | 9224879 | |
| Mycoplasma pneumoniae | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Cytomegalovirus | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 |
