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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | Type 1-fimbriae | Glycoside p-nitrophenyl alpha-D-mannopyranoside | Glycoconjugates | Patient with urinary tract infection | Binding | 6138149 | |
| Pseudomonas aeruginosa | Type 4-pili | Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins) | Glycoconjugates | Human epithelial cells | Binding | 9224879 | |
| Clostridium botulinum | Neurotoxin (type B) | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Clostridium botulinum | Unknown | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Escherichia coli | S-fimbriae (SfaA) | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Brain endothelial cells | Gal(3SO4)(b1-1)-alkylacylglycerol | Binding | 8098039 |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Galactose on sulfated glycolipids | Glycolipids | Gal | Binding | 12640357 | |
| Escherichia coli | PrsG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Clostridium tetani | Tetanus neurotoxin | Polysialogangliosides and other acidic lipids | Glycolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Clostridium tetani | TeNT | Polysialogangliosides and other acidic lipids | Glycolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Helicobacter pylori | Unknown | Epithelial type of glycolipid containing 2-hydroxy fatty acid | Glycolipids | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Monohexyl ceramides (MHCer) | Glycolipids | Binding | 16088272 | ||
| Mycoplasma pneumoniae | Unknown | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(3SO4)(b1-3)-alkylacylglycerol | Binding | 2470753 |
| Escherichia coli | (class II) | GL-II glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-II glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-IV glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | (class I/III) | GL-IV glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | (class I/III) | GL-II glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-II glycolipid | Glycolipids | Not Binding | 7721812 |
