Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Source Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Displaying entries 276 - 300 of 1840 in total
Species Pathogen Adherence Molecule Ligand Name ▲ Ligand Feature Target Source Glycan Sequence Binding PubMed ID
Escherichia coli Type 1-pili Collagen Glycoproteins Binding 12010488
Streptococcus gordonii SspA/SspB (AgI/II family) Collagen (type I) Glycoproteins humHn oral cavity (root dentine) Binding 16177339
Borrelia burgdorferi "DbpA, DbpB, Bgp" Collagen (type I) Glycoproteins Binding 16299269
Klebsiella pneumoniae MrkD-pili Collagen (type V) Glycoproteins Binding 10341176
Klebsiella pneumoniae MrkD-pili Collagen (type V) Glycoproteins Binding 12640357
Shigella dysenteriae Adhesins Colonic mucin Glycoproteins Colon Binding 11381327
Bordetella pertussis FHA (tail region) Complement receptor 3 (CR3) integrins Glycoproteins Macrophages Binding 11348687
Clostridium botulinum Neurotoxin (type B) Complex of synaptotagmin II and ganglioside GT1b or GD1a Glycoconjugates Binding 9712688
Clostridium botulinum Unknown Complex of synaptotagmin II and ganglioside GT1b or GD1a Glycoconjugates Binding 9712688
Streptococcus pneumoniae Adhesins D-Galactose Monosaccharides Vascular endothelial cells (only) Gal Binding 7752878
Pseudomonas aeruginosa PA-IL (51-kDa) D-Galactose Monosaccharides Gal Binding 15049333
Enterococcus faecalis EfaA (Lary family) D-Galactose-containing residues Saccharides Gal Binding 12640357
Streptococcus pneumoniae Adhesins D-Mannose Monosaccharides Type-II lung cells, Vascular endothelial cells Man Binding 7752878
Escherichia coli Type 1-pili D-Mannose Monosaccharides Bladder epithelium Man Binding 12010488
Escherichia coli FimCH-chaperone-adhesin complex D-Mannose Monosaccharides Bladder epithelium Man Binding 12010488
Pseudomonas aeruginosa PA-IIL D-Mannose Monosaccharides Man Binding 10967261
Pseudomonas aeruginosa PA-IIL (47-kDa) D-Mannose Monosaccharides Man Binding 15049333
Escherichia coli PrsG (class III) DSGG (Disialosyl galactosyl globoside, disialyl Gb5) Disialoglycosphingolipids Human kidney tissues NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Binding 9673272
Escherichia coli PapG (class I) DSGG (Disialosyl galactosyl globoside, disialyl Gb5) Disialoglycosphingolipids Human kidney tissues NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Binding 9673272
Escherichia coli P-fimbriae DSGG (Disialosyl galactosyl globoside, disialyl Gb5) Disialoglycosphingolipids Human kidney tissues NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Binding 9673272
Escherichia coli PapG (class II) DSGG (Disialosyl galactosyl globoside, disialyl Gb5) Disialoglycosphingolipids Human kidney tissues NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Binding 9673272
Shigella dysenteriae B subunit DSGG (Disialosyl galactosyl globoside, disialyl Gb5) Disialoglycosphingolipids Human erythrocytes NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Not Binding 3543013
Helicobacter pylori Neutrophil-activating proteins (150-kDa) DSPG (Disialosyl paragloboside) Disialoglycosphingolipids Human erythrocytes NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer Not Binding 9228091
Vibrio cholerae Cholera toxin DSPG (Disialosyl paragloboside) Disialoglycosphingolipids NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer Not Binding 7527546
Escherichia coli Heat-labile enterotoxin DSPG (Disialosyl paragloboside) Disialoglycosphingolipids NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer Not Binding 7527546

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