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MIRAGE
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Yersinia pestis | PsaA/B (pH-6 antigen) | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Cytomegalovirus | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Helicobacter pylori | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9169796 | |
| Rotavirus | Unknown | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 10816509 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2468365 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Glycosphingolipids | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 18701592 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Shigella dysenteriae | Unknown | unnamed ligand | Glycosphingolipids | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium freudenreichii | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
| Rotavirus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 11160731 | |
| Rotavirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 11160731 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 9712817 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2468365 |
