PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Actinomyces naeslundii | Adhesins | Asialofetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
Streptococcus sobrinus | SpaA (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
Bordetella pertussis | FHA (tail region) | Complement receptor 3 (CR3) integrins | Glycoproteins | Macrophages | Binding | 11348687 | |
Shigella dysenteriae | Adhesins | Colonic mucin | Glycoproteins | Colon | Binding | 11381327 | |
Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
Streptococcus sanguis | SsaB (Lral family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
Streptococcus sanguis | SsaB (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
Streptococcus gordonii | SspA/SspB (AgI/II family) | Collagen (type I) | Glycoproteins | humHn oral cavity (root dentine) | Binding | 16177339 | |
Streptococcus gordonii | SspA/SspB (AgI/II family) | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (in fluid and surface-associated phases) | Binding | 16177339 | |
Helicobacter pylori | Adhesins | Fetuin | Glycoproteins | Human leukocytes, Human neutrophils | Binding | 10569742 | |
Escherichia coli | K99 | Mucin | Glycoproteins | Intestinal cells | Binding | 7849044 | |
Neisseria meningitidis | Type 4-pili | Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans | Glycoproteins | Bovine | Binding | 16177210 | |
Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
Helicobacter pylori | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Human stomach associated with gastritis and peptic ulcer disease | Binding | 11007786 | |
Foot-and-mouth disease virus | VP1 (RGD peptide) | αvβ3 Integrin (independent of expression of Heparan sulfate on cell-sulface) | Glycoproteins | Extracellular matrix (ECM) | Binding | 9557639 | |
Foot-and-mouth disease virus | RGD motif of the VP1 GH loop | αvβ6 Integrin | Glycoproteins | Epithelial cells | Binding | 10799568 | |
Streptococcus agalactiae | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Neonatal meningitis | Binding | 11007786 | |
Pseudomonas aeruginosa | Adhesins | MUC1 mucin | Glycoproteins | Surface of chinese hamster ovary (CHO) cells | Binding | 11133508 | |
Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
Mycoplasma pneumoniae | Adhesins | Fetuin | Glycoproteins | Bovine erythrocytes | Binding | 2470754 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
GlyCosmos Portal v4.0.0
Last updated: August 19, 2024