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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus gordonii | CshA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus gordonii | CshA (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Mycoplasma gallisepticum | PlpA (pneumoniae-like protein; P65) | Fibronectin | Glycoproteins | Binding | 16495551 | ||
| Escherichia coli | CsgA (curli) | Fibronectin | Glycoproteins | Binding | 9973330 | ||
| Staphylococcus aureus | FnBPB (fibronectin binding protein) | Fibronectin | Glycoproteins | Binding | 1837266 | ||
| Staphylococcus aureus | FnBPA (fibronectin binding protein) | Fibronectin | Glycoproteins | Binding | 1837266 | ||
| Salmonella enteritidis | AgfA (curli) | Fibronectin | Glycoproteins | Binding | 9973330 | ||
| Mycoplasma gallisepticum | Hlp3 (HMW3-like protein) | Fibronectin | Glycoproteins | Binding | 16495551 | ||
| Helicobacter pylori | Adhesins | Five-sugar monosialoganglioside | Monosialoglycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (V3) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (VI2) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Pseudomonas aeruginosa | Unknown | Fucose | Monosaccharides | Respiratory tract | Fuc | Binding | 16564136 |
| Ralstonia solanacearum | RS-IIL (homologous to PA-IIL) | Fucose | Monosaccharides | Fuc | Binding | 16762477 | |
| Helicobacter pylori | Unknown | Fucose | Monosaccharides | Fuc | Binding | 8574698 | |
| Helicobacter pylori | Unknown | Fucose | Monosaccharides | Fuc | Binding | 16088272 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Vibrio cholerae | N-methylphenyl-alanine pili | Fucose ve mannose carbohydrate | Saccharides | Binding | 12640357 | ||
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse small intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Human skin | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Lactobacillus johnsonii | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse small intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Haemophilus parainfluenzae | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3413084 | |
| Pseudomonas aeruginosa | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3413084 |
