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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | Adhesins | GlcNAc(b1-3)Gal sequence | Saccharides | Human endothelial cells | GlcNAc(b1-3)Gal | Binding | 6886624 |
| Streptococcus pneumoniae | Unknown | unnamed ligand | Saccharides | GlcNAc(b1-3)Gal | Binding | 2885220 | |
| Escherichia coli | F17 | N-Acetylglucosamine | Monosaccharides | Urine (microvilli of the intestinal epithelium of ruminants) | GlcNAc | Binding | 16564136 |
| Cryptococcus neoformans | Adhesins | N-Acetylglucosamine | Monosaccharides | Human lung epithelial cell line (A549) | GlcNAc | Binding | 9453390 |
| Rabies virus | Unknown | N-Acetylglucosamine | Monosaccharides | Chicken embryo related cells | GlcNAc | Binding | 3583664 |
| Pasteurella haemolytica | 68-kDa proteins | N-Acetylglucosamine | Monosaccharides | Bronchial lavages of sheep with pneumonic pasteurelosis | GlcNAc | Binding | 10570221 |
| Escherichia coli | 20K-fimbriae | GlcNAc sequence | Saccharides | Human colon carcinoma Caco-2 cell line | GlcNAc | Binding | 8557360 |
| Escherichia coli | Type G-fimbriae | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 2885220 | |
| Escherichia coli | Fimbrial lectin (adhesin) protein GafD (25-kDa) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 7883703 | |
| Vibrio alginolyticus | CBP (chitin-binding proteins) 53-kDa | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 10049907 | |
| Vibrio cholerae | CBP (chitin-binding proteins) 36-kDa and 53-kDa | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 10049907 | |
| Vibrio harveyi | CBP (chitin-binding proteins) 53-kDa | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 10049907 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Not Binding | 14729696 | |
| Cytomegalovirus | Unknown | Glucuronyl paragroboside (GPG) | Oligoglycosylceramides | GlcA(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Mycoplasma pneumoniae | Unknown | Sulfated glucuronyl paragloboside | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | GlcA(3SO4)(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Bordetella pertussis | PT (subunits S2/S3 of B oligomer) | Glucosylceramide | Monoglycosylceramides | Human cilia of the respiratory epithelium | Glc(b1-1)Cer | Binding | 1729677 |
| Bordetella pertussis | Pertussis toxin | Glucosylceramide | Monoglycosylceramides | Human cilia of the respiratory epithelium | Glc(b1-1)Cer | Binding | 1729677 |
| Escherichia coli | F1C | Glucosylceramide (t18:0-h18:0) | Monoglycosylceramides | Rat intestine | Glc(b1-1)Cer | Binding | 11877427 |
| Mycoplasma pneumoniae | Unknown | Glucosylceramide | Monoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus casei | Unknown | Glucosylceramide | Monoglycosylceramides | Intestinal tract | Glc(b1-1)Cer | Binding | 8912650 |
| Escherichia coli | F1C | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Binding | 10816509 | |
| Actinobacillus pleuropneumoniae | LPS | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Binding | 10496867 | |
| Escherichia coli | F1C | Glucosylceramide (d18:1/t18:0-16:0-24:0) | Monoglycosylceramides | Porcine kidney | Glc(b1-1)Cer | Not Binding | 11877427 |
