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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | S-fimbriae | α-Sialyl-2,3-lactose-containing receptors | Saccharides | Binding | 11401961 | ||
| Listeria monocytogenes | Unknown | α-GalCer/CD1d tetramers | Glycoconjugates | V[alpha]14+ NK1.1- T cells in infected liver of mice | Binding | 16988270 | |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | von Willebrand factor (VWF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | von Willebrand factor (VWF) | Glycoproteins | Binding | 11393292 | ||
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | Neural cell lines | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 16564136 |
| Escherichia coli | K1 | unnamed ligand | Disaccharides | Endothelial cells | GlcNAc(b1-4)GlcNAc | Binding | 16564136 |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | unnamed ligand | Oligosaccharides | Polymorphonuclear leukocytes (PMNs) | Gal(b1-3)GalNAc | Binding | 7790078 |
| Streptococcus suis | PO | unnamed ligand | Oligosaccharides | human erythrocytes | Gal(a1-4)Gal | Binding | 7499414 |
| Escherichia coli | Type 1-fimbriae | unnamed ligand | Oligosaccharides | Urine | Man(a1-3)Man(a1-6)Man | Binding | 16564136 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Escherichia coli | S-fimbriae | unnamed ligand | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 11454740 | |
| Streptococcus sanguis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Mycoplasma pneumoniae | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Mycoplasma gallisepticum | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Streptococcus mitis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Sialoglycosphingolipids | NeuAc(a2-6)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Rotavirus | Unknown | unnamed ligand | Sialoglycosphingolipids | Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Streptococcus pneumoniae | Adhesins | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 6886624 | |
| Pseudomonas aeruginosa | Pili | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 8574698 |
