PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
---|---|---|---|---|---|---|---|
Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Dextran sulfate | Polysaccharides | Extracellular matrix (ECM) | Not Binding | 8764038 | |
Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Not Binding | 12704182 | ||
Escherichia coli | P-fimbriae | GL-IV glycolipid | Glycolipids | Not Binding | 7721812 | ||
Escherichia coli | (class I/III) | GL-IV glycolipid | Glycolipids | Not Binding | 7721812 | ||
Escherichia coli | (class I/III) | GL-II glycolipid | Glycolipids | Not Binding | 7721812 | ||
Escherichia coli | P-fimbriae | GL-II glycolipid | Glycolipids | Not Binding | 7721812 | ||
Escherichia coli | (class III) | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
Escherichia coli | P-fimbriae | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
Influenza virus | Unknown | Fetuin | Glycoproteins | Not Binding | 1740131 | ||
Helicobacter bilis | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
Helicobacter felis | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
Helicobacter pylori | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
Helicobacter canis | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
Helicobacter mustelae | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
Influenza virus | Unknown | Endothelial cell-specific molecule (ESM) | Proteoglycans | Not Binding | 1740131 | ||
Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | GlcNAc-6-P | Saccharides | Not Binding | 14729696 | ||
Clostridium botulinum | Botulinum neurotoxin (type C) | GD1b | Disialoglycosphingolipids | Presynaptic neuronal cells | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 18242046 |
Clostridium tetani | Tetanus toxin | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
Clostridium botulinum | BoNT/C (located within amino acid residues 1122-1290) | GD1b | Disialoglycosphingolipids | Presynaptic neuronal cells | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 18242046 |
Influenza virus | Hemagglutinin (HA) | GD1a | Disialoglycosphingolipids | Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11030743 |
Actinomyces naeslundii | Unknown | GD1b | Disialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
Clostridium tetani | Unknown | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
Escherichia coli | S-fimbriae (SfaA) | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Brain endothelial cells | Gal(3SO4)(b1-1)-alkylacylglycerol | Binding | 8098039 |
Escherichia coli | S-fimbriae | Sialyl galactoside units of cell surface glycoproteins | Glycoproteins | Vascular endothelial/epithelial cells of the choroid plexus, Ependyma cells lining the brain ventricles | NeuAc(a2-3)Gal(b1-4)Glc | Binding | 2893810 |
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Last updated: August 19, 2024