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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Vibrio cholerae | Cholera toxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Tetanus toxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Rotavirus | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | F1C | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Cytomegalovirus | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Escherichia coli | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | (class II) | GL-II glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-II glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-II glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/III) | GL-II glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class III) | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-IV glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/III) | GL-IV glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Polyoma virus | SV40 | GM1 | Monosialoglycosphingolipids | (broad range) | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | CS3 (coli surface 3)-fimbriae | GM1 | Monosialoglycosphingolipids | Intestinal epithelium, Rabbit intestine | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7822033 |
| Streptococcus pneumoniae | CTB-PsaA pentamers | GM1 | Monosialoglycosphingolipids | Serum, Saliva, Nasal/bronchial wash samples | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15358234 |
