Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Unknown | Heparan sulfate | Glycosaminoglycans | Binding | 16088272 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Heparan sulfate | Glycosaminoglycans | Binding | 16088272 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Dermatan sulfate | Glycosaminoglycans | Binding | 16299269 | ||
| Helicobacter pylori | Unknown | Heparan sulfate | Glycosaminoglycans | Binding | 16088272 | ||
| Mycoplasma pneumoniae | Unknown | GSLs containing terminal Gal(3SO4)β1-residues | Glycosphingolipids | Binding | 15973004 | ||
| Rotavirus | VP8 (spike protein) | Sialic acid(2-O-methyl-α-Neu5Gc (Neu5Gc2Me)) | Monosaccharides | Binding | 17306299 | ||
| Haemophilus influenzae | HifE (Pili family) | GM1(NeuAc/NeuGc) | Monosialoglycosphingolipids | Binding | 12640357 | ||
| Haemophilus influenzae | HifE (Pili family) | GM1(NeuAc/NeuGc) | Monosialoglycosphingolipids | Binding | 12640357 | ||
| Rotavirus | Unknown | Lactosylceramide (t18:0-h16:0-h24:0) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 15049333 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,3-galactose | Disaccharides | Gal(a1-3)Gal | Binding | 15049333 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,4-galactose | Disaccharides | Gal(a1-4)Gal | Binding | 15049333 | |
| Pseudomonas aeruginosa | PA-IIL | Blood group H antigen | Disaccharides | Fuc(a1-2)Gal | Binding | 16762477 | |
| Pseudomonas aeruginosa | PA-IL | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 10967261 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group H antigen | Disaccharides | Fuc(a1-2)Gal | Binding | 16762477 | |
| Norovirus | Unknown | Blood group H antigen | Disaccharides | Fuc(a1-2)Gal | Binding | 18599458 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Galactose on sulfated glycolipids | Glycolipids | Gal | Binding | 12640357 | |
| Escherichia coli | PrsG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | Type 1-fimbriae | Mannose-derived neoglycoproteins and dendrimers | Glycoproteins | Man | Binding | 16564136 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing Pk Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)Glc | Binding | 8440715 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
GlyCosmos Portal v4.4.0
Last updated: December 8, 2025