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Glycan Structure Repository
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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | F1C | Glucosylceramide (d18:1/t18:0-16:0-24:0) | Monoglycosylceramides | Porcine kidney | Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | PrsG (class III) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | PapG (class I) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | P-fimbriae | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Glucosylceramide | Monoglycosylceramides | Various sources | Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | PapG (class II) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Gonorrhoeae patients | Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
| Rotavirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 11160731 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2468365 | |
| Cytomegalovirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9780061 | |
| Propionibacterium freudenreichii | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2435422 | |
| Rotavirus | VP8 (spike protein) | Sialic acid(2-O-methyl-α-Neu5Gc (Neu5Gc2Me)) | Monosaccharides | Binding | 17306299 | ||
| Hantaan virus | SBA (soybean agglutinin) | N-Acetylgalactosamine | Monosaccharides | Vero E6/P388D1 cells | GalNAc | Binding | 10542025 |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | N-Acetylgalactosamine | Monosaccharides | Polymorphonuclear leukocytes (PMNs) | GalNAc | Binding | 7790078 |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | Galactose | Monosaccharides | Polymorphonuclear leukocytes (PMNs) | Gal | Binding | 7790078 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | N-Acetylgalactosamine | Monosaccharides | Intestinal cells | GalNAc | Binding | 15322032 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Entamoeba histolytica | Gal/GalNAc Lectins (260-kDa) | N-Acetylgalactosamine | Monosaccharides | c-Met on hepatocytes | GalNAc | Binding | 9878032 |
| Entamoeba histolytica | Gal/GalNAc Lectins (260-kDa) | Galactose | Monosaccharides | c-Met on hepatocytes | Gal | Binding | 9878032 |
| Hantaan virus | DBA (Dolichos biflorus agglutinin) | N-Acetylgalactosamine | Monosaccharides | Vero E6/P388D1 cells | GalNAc | Binding | 10542025 |
