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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | CS3 (coli surface 3)-fimbriae | GM2(NeuAc) | Monosialoglycosphingolipids | Intestinal epithelium, Rabbit intestine | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7822033 |
| Moraxella catarrhalis | Fimbriae | GM2(NeuAc) | Monosialoglycosphingolipids | Human pharyngeal epithelial cells | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Influenza virus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Helicobacter pylori | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human gastric mucosa | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2037054 |
| Streptococcus pneumoniae | CTB-PsaA pentamers | GM1 | Monosialoglycosphingolipids | Serum, Saliva, Nasal/bronchial wash samples | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15358234 |
| Sendai virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Hemagglutinin (HA) | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11030743 |
| Actinomyces naeslundii | Unknown | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Escherichia coli | K88ac | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Shigella dysenteriae | Adhesins | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11381327 | |
| Haemophilus influenzae | HifE (Pili family) | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 | |
| Vibrio cholerae | Cholera toxin | Extended GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Cholera toxin | B-GM1 | Monosialoglycosphingolipids | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Cholera toxin | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Vibrio cholerae | Cholera toxin | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Cholera toxin | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Clostridium perfringens | Delta toxin (type C) | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6260669 | |
| Clostridium tetani | Tetanus neurotoxin | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 |
