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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Klebsiella pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Streptococcus pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Staphylococcus aureus | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | Galactose | Monosaccharides | Polymorphonuclear leukocytes (PMNs) | Gal | Binding | 7790078 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Entamoeba histolytica | Gal/GalNAc Lectins (260-kDa) | Galactose | Monosaccharides | c-Met on hepatocytes | Gal | Binding | 9878032 |
| Actinomyces naeslundii | Adhesins | Galactose | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Gal | Binding | 11035744 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Clostridium botulinum | HA | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Rabies virus | Unknown | Galactose | Monosaccharides | Chicken embryo related cells | Gal | Binding | 3583664 |
| Entamoeba histolytica | Raft-like plasma membrane domains | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Pseudomonas aeruginosa | PA-I | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | Galactose | Monosaccharides | Gal | Binding | 10225860 | |
| Pseudomonas aeruginosa | PA-IL | Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Escherichia coli | Unknown | Galactose | Monosaccharides | Gal | Binding | 2885220 | |
| Entamoeba histolytica | 52-kDa recombinant fusion proteins | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Escherichia coli | 18-kDa fimbrial adhesin | Galactose derivatives | Saccharides | HEp-2 cells | Gal | Binding | 11368522 |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Galactose on sulfated glycolipids | Glycolipids | Gal | Binding | 12640357 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,3-galactose | Disaccharides | Gal(a1-3)Gal | Binding | 15049333 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,4-galactose | Disaccharides | Gal(a1-4)Gal | Binding | 15049333 | |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosyl sulfatide | Sulfoglycosphingolipids | Neural receptor | HSO3(-3)Gal(b1-1)Cer | Binding | 1871126 |
| Escherichia coli | S-fimbriae (SfaA) | Galactosyl sulfatide | Sulfoglycosphingolipids | Brain endothelial cells | Gal(3SO4)(b1-1)Cer | Binding | 8098039 |
| Mycoplasma pneumoniae | Unknown | Galactosyl sulfatide | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(3SO4)(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Galactosyl sulfatide | Sulfoglycosphingolipids | Gal(3SO4)(b1-1)Cer | Binding | 12628483 |
