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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | Adhesins | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 6886624 | |
| Pseudomonas aeruginosa | Pili | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 8574698 | |
| Actinomyces naeslundii | Unknown | unnamed ligand | Disaccharides | GalNAc(b1-3)Gal | Binding | 12628483 | |
| Streptococcus gordonii | Ca2+-independent lectins | Hs antigen | Glycoproteins | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc-HSA | Binding | 9393794 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing P1 Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)GlcNAc | Binding | 8440715 | |
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 16762477 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18701592 | |
| Haemophilus influenzae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Klebsiella pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Propionibacterium granulosum | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Streptococcus pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Staphylococcus aureus | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | F1C | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | F1C | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10816509 | |
| Actinobacillus pleuropneumoniae | LPS | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Binding | 10496867 | |
| Actinobacillus pleuropneumoniae | LPS | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10496867 | |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lactotriaosylceramide (Lc3) | Oligoglycosylceramides | GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 |
