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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Helicobacter pylori | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 16088272 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Lactotriaosylceramide (Lc3) | Oligoglycosylceramides | GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 | |
| Helicobacter pylori | Unknown | unnamed ligand | Oligosaccharides | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]Gal | Binding | 16564136 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group B-Lewis b (BLeb) antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A-Lewis b (ALeb) antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 15273394 | |
| Helicobacter pylori | Adhesins | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Binding | 12628483 | ||
| Helicobacter pylori | Unknown | Ganglio glycolipids | Glycosphingolipids | Binding | 16088272 | ||
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | Human erythrocytes | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM2(NeuAc) | Monosialoglycosphingolipids | Human brain | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | Human meconium | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialylparagloboside(NeuGc) | Monosialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl Lewis a (SLea) (GSL) | Monosialoglycosphingolipids | Human bile bladder tumor | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
