PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species ▼ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Escherichia coli | K88ab/K88ad | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
Escherichia coli | F1C | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
Escherichia coli | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
Escherichia coli | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
Escherichia coli | Unknown | unnamed ligand | Sialoglycosphingolipids | NeuAc(a2-6)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
Escherichia coli | F1C | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Not Binding | 10816509 | |
Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
Escherichia coli | A and B polypeptide subunits | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
Escherichia coli | SfaI-S | Sialic acid | Monosaccharides | Epithelial cells, Extracellular matrix (ECM) | Binding | 10732678 | |
Escherichia coli | S-fimbriae (SfaA) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Brain endothelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 8098039 |
Escherichia coli | P-fimbriae | Gb2 (Galabiosylceramide) | Diosylceramides | Urine | Gal(a1-4)Gal(b1-1)Cer | Binding | 16564136 |
Escherichia coli | P-pili | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
Escherichia coli | F1C | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Human neutrophils | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
Escherichia coli | PapG (class II) | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
Escherichia coli | PapG (class II) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Patient with septic infection or pyelonephritis | Gal(a1-4)Gal | Binding | |
Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Patient with septic infection or pyelonephritis | Gal(a1-4)Gal | Binding | |
Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
Escherichia coli | P-pili | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
Escherichia coli | PapG | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
Escherichia coli | PapG (class I) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
Escherichia coli | F1C | Glucosylceramide (t18:0-h18:0) | Monoglycosylceramides | Rat intestine | Glc(b1-1)Cer | Binding | 11877427 |
Escherichia coli | PapG (class I) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | CS3 (coli surface 3)-fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Intestinal epithelium, Rabbit intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7822033 |
Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
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Last updated: August 19, 2024