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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Escherichia coli | K88ab/K88ac/K88ad | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (V3) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (VI2) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | Type 1-pili | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Escherichia coli | FimCH-chaperone-adhesin complex | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Escherichia coli | FimH | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Escherichia coli | Type 1-pili | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Escherichia coli | FimH | CD48 | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Collagen | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | CD48 | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Collagen | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Laminin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Laminin | Glycoproteins | Binding | 12010488 | ||
| Moraxella catarrhalis | Fimbriae | GM2(NeuAc) | Monosialoglycosphingolipids | Human pharyngeal epithelial cells | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Moraxella catarrhalis | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Other than pharyngeal epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Moraxella catarrhalis | Fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human pharyngeal epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
