PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | De-N-sulfated heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
Human immunodeficiency virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human T cells | Binding | 9420059 | |
Chlamydia trachomatis | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | HeLa cells | Binding | 9420059 | |
Herpes simplex virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human cervical cells | Binding | 9420059 | |
Neisseria gonorrhoeae | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human epithelial cells | Binding | 9420059 | |
Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 9557639 | |
Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate A | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Dermatan sulfate | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Chondroitin 4-sulfate (C-4S) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate C | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
Borrelia burgdorferi | Unknown | Heparin (completely desulfated, N-acetylated) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Escherichia coli | S-fimbriae | Sialyl galactoside units of cell surface glycoproteins | Glycoproteins | Vascular endothelial/epithelial cells of the choroid plexus, Ependyma cells lining the brain ventricles | NeuAc(a2-3)Gal(b1-4)Glc | Binding | 2893810 |
Norovirus | Unknown | Sialylated type 2 chain conjugates (S-type 2-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
Norovirus | Unknown | Sialyl Lewis x (SLex-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
Helicobacter pylori | Fibrillar hemmagglutinin | N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence | Glycoproteins | Gastric epithelium, Mucus layer of the stomach | NeuAc(a2-3)Gal | Binding | 2459065 |
Streptococcus gordonii | Ca2+-independent lectins | Hs antigen | Glycoproteins | NeuAc(a2-3)Gal(b1-4)Glc-HSA | Binding | 9393794 | |
Adeno-associated virus | Unknown | Glycoproteins with α2,3 N-linked sialic acid | Glycoproteins | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16940521 | |
Mycoplasma pneumoniae | Unknown | Glycoproteins with terminal NeuAcα3Galβ4GlcNAc-sequences | Glycoproteins | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 15973004 | |
Parvovirus | Unknown | O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA) | Glycoproteins | Human erythrocytes | Binding | 15750863 | |
Streptococcus gordonii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
Rubulavirus | Unknown | N-linked sialylated glycoproteins | Glycoproteins | Pig neurons, glial cells | Binding | 16459111 |
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Last updated: August 19, 2024