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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycoproteins | Glycoproteins | Binding | 15973004 | ||
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Human serum albumin | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 19054801 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Human serum albumin | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 19054801 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Escherichia coli | Type 1-fimbriae | Mannose-derived neoglycoproteins and dendrimers | Glycoproteins | Man | Binding | 16564136 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing Pk Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)Glc | Binding | 8440715 | |
| Actinomyces naeslundii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Actinomyces naeslundii | Adhesins | Asialofetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Streptococcus sobrinus | SpaA (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Bordetella pertussis | FHA (tail region) | Complement receptor 3 (CR3) integrins | Glycoproteins | Macrophages | Binding | 11348687 | |
| Shigella dysenteriae | Adhesins | Colonic mucin | Glycoproteins | Colon | Binding | 11381327 | |
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sanguis | SsaB (Lral family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sanguis | SsaB (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Collagen (type I) | Glycoproteins | humHn oral cavity (root dentine) | Binding | 16177339 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (in fluid and surface-associated phases) | Binding | 16177339 | |
| Helicobacter pylori | Adhesins | Fetuin | Glycoproteins | Human leukocytes, Human neutrophils | Binding | 10569742 |
