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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Phenyl-β-thiogalactoside | Saccharides | Binding | 15049333 | ||
| Clostridium botulinum | Botulinum neurotoxin (type D) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Presynaptic neuronal cells | Binding | 18242046 | |
| Pseudomonas aeruginosa | exoenzyme S | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Epithelial cells | Binding | 9224879 | |
| Campylobacter upsaliensis | 5 bacterial surface proteins (50 to 90-kDa) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | HEp-2 cells | Binding | 8926069 | |
| Clostridium botulinum | BoNT/D (two lysine residues (K1117 and K1135 in Hc/D1)) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Presynaptic neuronal cells | Binding | 18242046 | |
| Helicobacter pylori | Unknown | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Binding | 16088272 | ||
| Campylobacter upsaliensis | Unknown | Phosphatidylserine (PS) | Non-glycosylated Lipids | Binding | 8926069 | ||
| Helicobacter pylori | Unknown | Phospholipids | Non-glycosylated Lipids | Binding | 16088272 | ||
| Escherichia coli | CsgA (curli) | Plasminogen | Glycoproteins | Binding | 9973330 | ||
| Salmonella enteritidis | AgfA (curli) | Plasminogen | Glycoproteins | Binding | 9973330 | ||
| Shigella dysenteriae | Stx | Platelet-specific GSL (Stx band 0.03) | Glycosphingolipids | Human platelets | Binding | 9712788 | |
| Poliovirus | Unknown | Poliovirus receptors (PVRs) | Glycoproteins | Binding | 12663789 | ||
| Plasmodium falciparum | Unknown | Polylactosamine of band 3 | Polysaccharides | Binding | 8574698 | ||
| Clostridium tetani | Tetanus neurotoxin | Polysialogangliosides and other acidic lipids | Glycolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Clostridium tetani | TeNT | Polysialogangliosides and other acidic lipids | Glycolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Cytomegalovirus | Unknown | SB1a (gangliotetraosylceramide bis-sulfate; SD1a) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-3)GalNAc(b1-4)[HSO3(-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Cytomegalovirus | Unknown | SGLPG (Sulfated glucuronyl lactosaminyl paragloboside) | Sulfoglycosphingolipids | HSO3(-3)GlcA(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Cytomegalovirus | Unknown | SGPG (Sulfated glucuronyl paragloboside) | Sulfoglycosphingolipids | HSO3(-3)GlcA(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Actinomyces naeslundii | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Vero cells | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Escherichia coli | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Parvovirus | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Actinomyces viscosus | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Vero cells | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Human kidney | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Shigella dysenteriae | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 |
