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MIRAGE
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | S-fimbriae | α-Sialyl-2,3-lactose-containing receptors | Saccharides | Binding | 11401961 | ||
| Vibrio cholerae | N-methylphenyl-alanine pili | Fucose ve mannose carbohydrate | Saccharides | Binding | 12640357 | ||
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | GlcNAc-6-P | Saccharides | Not Binding | 14729696 | ||
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuGc3-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Mycoplasma pneumoniae | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | F1C | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Dog intestine | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Shigella dysenteriae | B subunit | unnamed ligand | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Human skin | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces naeslundii | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Influenza virus | Unknown | NeuAc6-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | NeuAc(a2-6)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Propionibacterium freudenreichii | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Propionibacterium granulosum | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Escherichia coli | PrsG (class III) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class II) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | Human erythrocytes | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
