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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Vero cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15292153 |
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Shigella dysenteriae | Stx | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Ubiquitously expressed in most tissues (e.g. human erythrocytes/endothelium/kidney/platelet) | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9712788 |
| Actinomyces viscosus | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Lactobacillus johnsonii | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse feces | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Shigella dysenteriae | B subunit | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Human type B erythrocytes | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 3519828 |
| Shigella dysenteriae | B subunit | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | HeLa cells, Rabbit jejunul mucosa | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3519828 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Shigella dysenteriae | B subunit | Gal-Gb3 | Oligoglycosylceramides | Rat small intestine | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Shigella dysenteriae | B subunit | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Shigella dysenteriae | B subunit | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes, Rat small intestine | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Pseudomonas aeruginosa | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Cystic fibrosis patients | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 |
| Pseudomonas aeruginosa | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Lung | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Lactobacillus casei | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Intestinal tract | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
| Lactobacillus casei | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Intestinal tract | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
| Pseudomonas aeruginosa | Flagellin | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Candida albicans | "Extracellular polymeric material, acid proteinase, chitin" | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Pseudomonas aeruginosa | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Apical membrane of cystic fibrosis epithelia | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7708767 |
| Actinomyces naeslundii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Vero cells | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Pseudomonas cepacia | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Lung | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
