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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
| Escherichia coli | A and B polypeptide subunits | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-IIb)) | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | A and B polypeptide subunits | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | A and B polypeptide subunits | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | A and B polypeptide subunits | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3284526 | |
| Escherichia coli | Verotoxin (2) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3284526 | |
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3284526 | |
| Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas cepacia | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas aeruginosa | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Lung | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas cepacia | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Lung | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Escherichia coli | S-fimbriae | Sialyl galactoside units of cell surface glycoproteins | Glycoproteins | Vascular endothelial/epithelial cells of the choroid plexus, Ependyma cells lining the brain ventricles | NeuAc(a2-3)Gal(b1-4)Glc | Binding | 2893810 |
| Escherichia coli | PapG | alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose | Disaccharides | Uroepithelial cells | Gal(a1-4)Gal | Binding | 2886993 |
| Streptococcus sanguis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Mycoplasma pneumoniae | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Mycoplasma gallisepticum | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Streptococcus mitis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Escherichia coli | K99 | unnamed ligand | Oligosaccharides | NeuGc(a2-3)Gal(b1-4)Glc | Binding | 2885220 | |
| Escherichia coli | Type G-fimbriae | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 2885220 | |
| Klebsiella pneumoniae | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 |
