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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Norovirus | Unknown | Terminal N-Acetylgalactosamine residue in an alpha linkage | Saccharides | Oyster digestive tissues | Binding | 16707048 | |
| Reovirus | Unknown | Sialic acid (α2,3) | Saccharides | Most organs including the central nervous system/heart/liver | NeuAc(a2-3) | Binding | 18216114 |
| Escherichia coli | CFA/1 | Sialic acid (α2,8) | Saccharides | Intestinal cells | NeuAc(a2-8) | Binding | 16564136 |
| Theiler's murine encephalomyelitis virus | VP2 amino acids on puff B | Sialic acid (α2,3) | Saccharides | Central nervous system | NeuAc(a2-3) | Binding | 16575521 |
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:2 | Not Binding | 9712794 |
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:1 | Binding | 9712794 |
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Not Binding | 9712794 |
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:1 | Binding | 9712794 |
| Enterococcus faecalis | EfaA (Lary family) | D-Galactose-containing residues | Saccharides | Gal | Binding | 12640357 | |
| Histoplasma capsulatum | Lectin-like component | unknown carbohydrate ligand | Saccharides | Human erythrocytes | Binding | 19547878 | |
| Haemophilus influenzae | HMW1 | unknown carbohydrate ligand | Saccharides | Human epithelial cells (respiratory tract) | Binding | 10341176 | |
| Haemophilus influenzae | HMW2 | unknown carbohydrate ligand | Saccharides | Human epithelial cells (respiratory tract) | Binding | 10341176 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | unknown carbohydrate ligand | Saccharides | Platelet | Binding | 16177339 | |
| Escherichia coli | AC/I-fimbriae (S-fimbrial family) | unknown carbohydrate ligand | Saccharides | Septicemic avian epithelial cells | Binding | 10992500 | |
| Streptococcus pneumoniae | PsaA (Lary family) | unknown carbohydrate ligand | Saccharides | Nasopharynx, Alveolar epithelial cells | Binding | 10341176 | |
| Streptococcus gordonii | Hsa | unknown carbohydrate ligand | Saccharides | Platelet | Binding | 16177339 | |
| Haemophilus influenzae | Hia | unknown carbohydrate ligand | Saccharides | Human conjunctival cells (respiratory tract) | Binding | 10341176 | |
| Actinomyces odontolyticus | Unknown | unknown carbohydrate ligand | Saccharides | Tongue | Binding | 9712794 | |
| Streptococcus pneumoniae | PclA (pneumococcal collagen-like protein A) | unknown carbohydrate ligand | Saccharides | Detroit 562/A549 cell lines | Binding | 18557785 | |
| Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Phenyl-β-thiogalactoside | Saccharides | Binding | 15049333 | ||
| Escherichia coli | S-fimbriae | α-Sialyl-2,3-lactose-containing receptors | Saccharides | Binding | 11401961 | ||
| Vibrio cholerae | N-methylphenyl-alanine pili | Fucose ve mannose carbohydrate | Saccharides | Binding | 12640357 | ||
| Anaplasma marginale | "MSP1a, MSP1b, MSP2" | unknown carbohydrate ligand | Saccharides | Binding | 16299269 | ||
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:1 | Not Binding | 9712794 |
