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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus mutans | Ag I/II (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Dental plaque (caries-associated) | Binding | 11007786 | |
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus pneumoniae | CTB-PsaA pentamers | GM1 | Monosialoglycosphingolipids | Serum, Saliva, Nasal/bronchial wash samples | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15358234 |
| Streptococcus pneumoniae | Adhesins | N-Acetylgalactosamine | Monosaccharides | Type-II lung cells, Vascular endothelial cells | GalNAc | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | D-Mannose | Monosaccharides | Type-II lung cells, Vascular endothelial cells | Man | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | D-Galactose | Monosaccharides | Vascular endothelial cells (only) | Gal | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine-activated cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12640357 |
| Streptococcus pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine activated epithelial and endothelial cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 |
| Streptococcus pneumoniae | Unknown | unnamed ligand | Oligosaccharides | Chinchilla tubotympanum | Gal(b1-4)GlcNAc(b1-3)Gal(b | Binding | 1298868 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus pneumoniae | Adhesins | GlcNAc(b1-3)Gal sequence | Saccharides | Human endothelial cells | GlcNAc(b1-3)Gal | Binding | 6886624 |
| Streptococcus pneumoniae | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Streptococcus pneumoniae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Streptococcus pneumoniae | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3413084 | |
| Streptococcus pneumoniae | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3413084 | |
| Streptococcus pneumoniae | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Streptococcus pneumoniae | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Streptococcus pneumoniae | Unknown | Trisaccharides | Oligosaccharides | GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 | |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 |
