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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Ralstonia solanacearum | RS-IIL (homologous to PA-IIL) | Mannose | Monosaccharides | Man | Binding | 16762477 | |
| Ralstonia solanacearum | RS-IIL (homologous to PA-IIL) | Fucose | Monosaccharides | Fuc | Binding | 16762477 | |
| Pseudomonas aeruginosa | PA-IIL | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 16762477 | ||
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 16762477 | |
| Pseudomonas aeruginosa | PA-IIL | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
| Pseudomonas aeruginosa | PA-IIL | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16762477 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16762477 | |
| Adeno-associated virus | Unknown | Glycoproteins with α2,3 N-linked sialic acid | Glycoproteins | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16940521 | |
| Adeno-associated virus | Unknown | Glycoprotein with α2,6 N-linked sialic acid | Glycoproteins | NeuAc(a2-6)Gal(b1-4)GlcNAc | Binding | 16940521 | |
| Adeno-associated virus | Unknown | NeuAcα2-3GalNAcβ1-4GlcNAc | Oligosaccharides | NeuAc(a2-3)GalNAc(b1-4)GlcNAc | Binding | 16940521 | |
| Helicobacter pylori | Phe147 in HpaA (Helicobacter pylori adhesin A) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 16953581 | |
| Leptospira interrogans | Lsa24 | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 16954400 | |
| Listeria monocytogenes | Unknown | α-GalCer/CD1d tetramers | Glycoconjugates | V[alpha]14+ NK1.1- T cells in infected liver of mice | Binding | 16988270 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | Respiratory epithelial cells | Binding | 17106803 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Lactose | Disaccharides | Intestinal epithelial cells (T84) | Gal(b1-4)Glc | Binding | 17156748 |
| Clostridium botulinum | HA | Lactose | Disaccharides | Intestinal epithelial cells (T84) | Gal(b1-4)Glc | Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylgalactosamine | Monosaccharides | Intestinal epithelial cells (T84) | GalNAc | Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylgalactosamine | Monosaccharides | Intestinal epithelial cells (T84) | GalNAc | Binding | 17156748 |
| Clostridium botulinum | HA | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
