GPVI-mediated activation cascade

Summary
Species
Bos taurus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPADPGPVI:FceRI gamma:FYN:LYN:Collagen type IGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type IGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:SYKSYKGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:p-Y348-SYKp-Y348-SYKGTPGDPVAV1 Rho/Rac effectors:GDPVAV1 Rho/Rac effectors:GTPVAV2 Rho/Rac effectors:GTPVAV2 Rho/Rac effectors:GDPVAV3 Rho/Rac effectors:GTPVAV3 Rho/Rac effectors:GDPF1MZ60LATLCP2Q08DS6PLCG2p-PLCG2p-SLP-76:VAVVAV1,2,3PIP2DAGIP3PI3K gammaPI3K betaPIP3PDPK1:PIP3PDPK1SHP1,SHP2G6B:PTPN6,PTPN11G6BPDPNCLEC1B dimer:PDPNCLEC1B dimerp-Y7-CLEC1B dimer:PDPNp-Y7-CLEC1B dimer:PDPN:SYK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025