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MIRAGE
Trafficking and processing of endosomal TLR

Summary
Species
Bos taurus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TLR7/8/9ATP-bound Gp96 dimer:CNPY3:TLR7/8/9CNPY3ATPApo-GP96 dimerfolded FL-TLR7/8/9ADPintracellular TLR3/7/8/9intracellular TLR:UNC93B1E1BBH4intracellular TLR:UNC93B1FL-TLR9 dimerC-ter-TLR9 dimerC-ter TLR7 dimerFL-TLR7 dimerN-ter TLR9 dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P07688 Cathepsin B
  • CTSB
 view
P25326 Cathepsin S
  • CTSS
 view
P25975 Procathepsin L
  • CTSL
  • CTSL1
 view
Q0P5N1 Protein canopy homolog 3
  • CNPY3
 view
Q5E968 Cathepsin K
  • CTSK
 view
Q95M18 Endoplasmin
  • GRP94
  • HSP90B1
  • HSPC4
  • TRA1
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025