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MIRAGE
MHC class II antigen presentation

Summary
Species
Bos taurus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HLA II beta chainMHC II alpha beta heterodimerHLA II alpha chainCANXalpha beta dimer:Ii trimer:calnexinInvariant chain trimer2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimerCOPIINonameric complex in COPII vesicleNonameric complexNonameric complexNonameric complexArf1-GTPAP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complexDynaminClathrin TriskelionAP-1 ComplexAP-1 Clathrin coated nonameric complexArf1-GDPPiGTPGDPTGN-lysosome vesicle with nonameric complexNonameric complexMHC class II alpha/beta/Ii nonamerMHC class II alpha/beta/Ii nonamerClathrin coated MHC class II alpha/beta/Ii nonamerClathrin:AP-2 complexSH3GL2H2OClathrin coated MHC class II alpha/beta/Ii nonamerClathrin:AP2 complexNonameric complexSH3GL2MHC II:lip22 nonamerMHC II:lip10 nonamerMHC II:CLIPHLA-DM/HLA-DOpeptide free MHC II:HLA-DMCD74Antigenunfolded antigenMHC class II epitopespeptide loaded MHC class IIARP-1ATPKinesins:Dynactin:microtubuleRAB7:RILP:ORP1L complexpeptide loaded MHC class IISPTBN2ADPDynein:Dynactin:microtubuleLAG3LAG3:MHC IIMHC class II alpha/beta dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 7 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
A6QPN6 Gamma-interferon-inducible lysosomal thiol reductase
  • IFI30
 view
F1MMR6 Cathepsin D
  • CTSD
 view
P07688 Cathepsin B
  • CTSB
 view
P25326 Cathepsin S
  • CTSS
 view
P25975 Procathepsin L
  • CTSL
  • CTSL1
 view
Q3T0I2 Pro-cathepsin H
  • CTSH
 view
Q5E968 Cathepsin K
  • CTSK
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025