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MIRAGE
Extra-nuclear estrogen signaling

Summary
Species
Bos taurus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TPNHH2OH+TPNL-CitO2NOL-ArgAdoMetMe-PalmS-ESRsPalmS-ESRsSAHESRsESRs:HSBP1 oligomerHSBP1 oligomerCoA-SHPALM-CoAPalmS-ESRsCAVsPalmS-ESRs:CAVsCAVsESTGESTG:Me-PalmS-ESR dimersSTRNPalmS-ESRs:STRN:ESTGESRs:STRN:ESTGESTG:ESRs:STRN:heterotrimeric G(i) proteinHeterotrimeric G-protein Gi (inactive)G-protein alpha (i):GDPG-protein beta-gamma complexE1BIM8ESRs:STRN:ESTG:MyrG-SRCATPADPESRs:STRN:ESTG:MyrG-pY419-SRCESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alphaPI3K alphaMe260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alphaMe260-ESR1:STRN:ESTG: MyrG-pY419 SRC:PI3Kalpha:pY-PTK2A0A3Q1N508SHC1ESTG:ESR1:p-3Y-IGF1R:SHC1ESTG:Me260-ESR1 dimerp-Y1161,1165,1166-IGF1RHBEGFHBEGFHBEGFPTK2EGF-like ligands:p-6Y EGFR:PTK2EGF-like ligands:p-6Y EGFR dimerEGF-like ligands:p-6Y EGFR dimer:p-Y397 PTK2SPGS1PS1PR3S1P:S1PR3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 2 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P49884 Estrogen receptor
  • ESR
  • ESR1
  • NR3A1
 view
P52176 Matrix metalloproteinase-9
  • MMP9
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025