Interferon alpha/beta signaling

Summary
Species
Bos taurus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
IFNA/BIFNA/B:IFNAR2:JAK1:STAT2IFNAR2:JAK1:STAT2type 1 interferon analogsIFNAR2:JAK1:STAT2:type 1 interferon analogsIFNAR2:JAK1:STAT2:JAK1,2 inhibitorsJAK1,2 inhibitorsIFNAR1:TYK2IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2IFNAR1:TYK2:TYK2 inhibitorsTYK2 inhibitorsATPADPIFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2STAT2IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1p-STAT2:p-STAT1IRF9ISGF3p-Y701-STAT1-1 dimerSTAT1KPNA1p-STAT1 dimer:KPNA1p-STAT1 dimer, ISGF3KPNB1p-STAT1 dimer:KPNA1:KPNB1ISGF3:KPNA1:KPNB1KPNA1ISGF3KPNB1p-Y701-STAT1:KPNA1:KPNB1p-Y701-STAT1 dimerRNASEL dimerABCE1:RNASEL dimerABCE1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q04790 Interferon alpha/beta receptor 1
  • IFNAR
  • IFNAR1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025