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G alpha (i) signalling events

Summary
Species
Canis familiaris
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Heterotrimeric G-protein Gi (inactive)Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive)Ligand:GPCR complexes that activate GiGTPGDPLigand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active)G alpha (i): GTPG-protein beta-gamma complexG-alpha(t):GTP:G-beta-gamma:OpsinsG-alpha(t):GDP:G-beta-gamma:OpsinsG-protein alpha (i):GDPATPG protein alpha (i):GTP:p-Y419-SRCG alpha (i):GTP:SRC-1ADPp-Y419-SRCRGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21G alpha (i):GTP:RGSG alpha (i):GDP:RGSPiG-alpha(t)-GDP:G-beta-gammaOpsins:photonG-alpha(t)-GTP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025