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MIRAGE
Integrin signaling

Summary
Species
Drosophila melanogaster
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RAP1:GDPRAP1:GTPGDPGTPPIP2Rap1-GTP:PIP2:RIAMpicoTalin:RIAM complexrheaIntegrin alphaIIb beta3:p-Y530-SRC:CSKIntegrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complexHmlFocal complexIntegrin binding divalent cationsTalin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK)Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC)CSKH2OPiTalin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC)ADPATPTalin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC)Integrin alpha2bbeta3Integrin alpha IIb p(T779)-beta 3ShcIntegrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHCIntegrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHCQ9V3C8SYKTalin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYKTalin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P11584 Integrin beta-PS
  • l(1)mys
  • mys
  • olfC
 view
P12080 Integrin alpha-PS2
  • if
 view
P83097 Putative inactive tyrosine-protein kinase Wsck
  • Wsck
 view
Q27591 Integrin beta-nu
  • Itgbetanu
  • Itgbn
  • beta-nu
  • betaInt-nu
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025