Cargo recognition for clathrin-mediated endocytosis

Summary
Species
Drosophila melanogaster
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
AP-2 ComplexAP-2:cargoAP-2 cargoAP2:chlorpromazinechlorpromazineubiquitinated cargoEPS15,EPN1,EPN2:ubiquitinated cargoEPS15,EPN1,EPN2UBQLN2,1UNQLNs:UIM proteinsARRBARRB:ARRB-binding GPCRsARRB-binding GPCRsARBBs:ARBB-binding GPCRs:clathrin-coated pitPI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1AGFG1AGFG1:VAMP7Vamp7SYT dimersSTON2,1:SYT dimersstnBNedd8stnBTOR1 hexamerNEDD8-STONs:TOR1 hexamer:COP9COP9VAMP2,3,8PICALM:VAMP2,3,8lap
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024