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MIRAGE
Common Pathway of Fibrin Clot Formation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
factor Xafactor Xa:Factor Xa inhibitorsFactor Xa inhibitors10xCbxE-F2FIIa10xCbxE-F2(44-327)F5F5(738-1573)factor VaVa:Xafactor XaVa:Xa:Factor Xa inhibitorsFibrinogenFGB(31-44)FGA(20-35)fibrin monomerfibrin multimerfactor XIIIfactor XIII cleaved tetramerF13A1(1-37)factor XIIIaF13BCa2+fibrin multimer, crosslinkedNH4+SERPINC1 activatorsSERPINC1:SERPINC1 activatorsAT3thrombin:SERPINC1:SERPINC1 activatorsthrombin:cleaved SERPINC1:SERPINC1 activatorsthrombin:cleaved SERPINC1activated thrombin:thrombomodulinTHBDEPCRPROCR:Protein CProtein CPROC(200-211)PROCR:Activated protein CActivated protein Cprotein SActivated protein C:Protein SF5(535-737)factor Vi intermediate formF5(335-534)factor Vifactor VIIIaF8(356-372)F8(582-640)Inactivated factor VIIISERPIND1activated thrombin (factor IIa):SERPIND1activated thrombin (factor IIa)SERPINE2:GAG:activated thrombin (factor IIa)SERPINE2:GAGSERPINA5:Activated protein CSERPINA5PROCR:Activated protein C:F2RF2R(42-425)PROCR(18-?):Activated protein CsEPCRPRTN3:CD177PROCR(18-?):PRTN3:CD177
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 11 - 20 of 20 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P05160 Coagulation factor XIII B chain
  • F13B
 view
P05546 Heparin cofactor 2
  • HCF2
  • SERPIND1
 view
P07093 Glia-derived nexin
  • PI7
  • PN1
  • SERPINE2
 view
P07204 Thrombomodulin
  • THBD
  • THRM
 view
P07225 Vitamin K-dependent protein S
  • PROS
  • PROS1
 view
P12259 Coagulation factor V
  • F5
 view
P24158 Myeloblastin
  • MBN
  • PRTN3
 view
P25116 Proteinase-activated receptor 1
  • CF2R
  • F2R
  • PAR1
  • TR
 view
Q8N6Q3 CD177 antigen
  • CD177
  • NB1
  • PRV1
 view
Q9UNN8 Endothelial protein C receptor
  • EPCR
  • PROCR
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025