Sphingolipid de novo biosynthesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
H+CYB5B:Fe3+O2FAH2OCYB5B:Fe2+2-OH FASer3-ketosphingoidCoA-SHacyl-CoACO2TPNHTPNsphingoidDHCE(4E)-CERAphytoceramideATPADPCERT1-2COL4A3BPCOL4A3BPPPM1L:VAPA/B dimerp-S,S132,T-CERT1-2:PPM1L:VAPA/B trimerCERT1-2:PPM1L:VAPA/B trimerPiCERAceramide:CERT1-2:PPM1L:VAPA/B trimerceramide:CERT1-2CERADAGPCSPHMCERADAGPCSPHMC16DH CERCPEPEDAGSPGS1PSPHK2SPHK2:SPHK2 inhibitorsSPHK2 inhibitorsS1PS1PS1P
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025