Polymerase switching on the C-strand of the telomere

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
DCC1CTF18 complexCTF18CTF8RFC3CTF18-RFC(7s) complexRFC4RFC2RFC5RNA primer:DNA primer:G-strand extended telomere:POLA:primaseRFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere endRFC,(CFT18-RFC)primosomeCST complexH2OADPPiATPRFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimerPCNA homotrimerRNA primer-DNA primer:G-strand extended telomere:PCNADNA Polymerase delta tetramerProcessive complex loaded on telomere
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025