Peptide hormone biosynthesis

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-209952
PubChem
R-HSA-209952
Description
  • Peptide hormones are peptides that are secreted directly into the blood stream (endocrine hormones). They are synthesized as precursors that require proteolytic processing (not discussed here) to generate the biologically active peptides that mediate neurotransmission and hormonal action. Glycoprotein hormones (those which include carbohydrate side-chains) and the processing of corticotropin are annotated here.
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 2 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01189 Pro-opiomelanocortin
  • POMC
view
P29120 Neuroendocrine convertase 1
  • NEC1
  • PCSK1
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026