Synthesis of 15-eicosatetraenoic acid derivatives

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-2142770
PubChem
R-HSA-2142770
Description
  • The 15-eicosatetraenoates: 15-hydroperoxy-eicosatetraenoate (15-HpETE), 15-hydroxyeicosatetraenoate (15-HETE) and 15-oxo-eicosatetraenoate (15-oxoETE) are formed after the initial step of arachidonate oxidation by the arachidonate 15-lipoxygenases (ALOX15 and ALOX15B) (Buczynski et al. 2009, Vance & Vance 2008).
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
P35354 Prostaglandin G/H synthase 2
  • COX2
  • PTGS2
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026