SUMOylation of DNA damage response and repair proteins

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
BLMUBE2IUBE2I:SUMO2,UBE2I:SUMO3BLM_HUMANBRCA1SUMO1:C93-UBE2IBRCA1_HUMANBRCA1_HUMANCentrin-2CETN2Cohesin ComplexSUMOylated CohesinHERC2HERC2_HUMANMDC1MDC1_HUMANMDC1_HUMANPARP1monoSUMO1-K203,K486-PARP1polySUMO2,3-K203,K486-PARP1PMLPML_HUMANPML_HUMANUBC9_HUMANUBC9_HUMANPML_HUMANRAD52_HUMANRAD52RN168_HUMANRNF168RPA1RP-ASP100_HUMANSP100SP100_HUMANmonoSUMO1-K330-TDGTDGpolySUMO2,3-K330-TDGWRNWRN_HUMANXRCC4monoSUMO1-K210-XRCC4XPC_HUMANXPC
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 11 - 20 of 50 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P35227 Polycomb group RING finger protein 2
  • MEL18
  • PCGF2
  • RNF110
  • ZNF144
view
P35658 Nuclear pore complex protein Nup214
  • CAIN
  • CAN
  • KIAA0023
  • NUP214
view
P37198 Nuclear pore glycoprotein p62
  • NUP62
view
P38398 Breast cancer type 1 susceptibility protein
  • BRCA1
  • RNF53
view
P49790 Nuclear pore complex protein Nup153
  • NUP153
view
P49792 E3 SUMO-protein ligase RanBP2
  • NUP358
  • RANBP2
view
P54132 RecQ-like DNA helicase BLM
  • BLM
  • RECQ2
  • RECQL3
view
P55735 Protein SEC13 homolog
  • D3S1231E
  • SEC13
  • SEC13A
  • SEC13L1
  • SEC13R
view
P57740 Nuclear pore complex protein Nup107
  • NUP107
view
P63165 Small ubiquitin-related modifier 1
  • SMT3C
  • SMT3H3
  • SUMO1
  • UBL1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025