Apoptotic cleavage of cell adhesion proteins

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
CDH1CDH1CDH1DSG3DSG3(782-999)DSG3(50-781)DSG2DSG2(?-1118)DSG1DSG1(889-1049)DSG1(50-888)PKP1PKP1(?-?)TJP1ZO-1TJP2TJP2(?-?)beta-cateninCTNNB1(1-115)CTNNB1(116-376)DSPDSP(?-?)OCLNOCLN(321-522)OCLN(1-320)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 9 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P12830 Cadherin-1
  • CDH1
  • CDHE
  • UVO
view
P15924 Desmoplakin
  • DSP
view
P32926 Desmoglein-3
  • CDHF6
  • DSG3
view
P35222 Catenin beta-1
  • CTNNB
  • CTNNB1
view
Q02413 Desmoglein-1
  • CDHF4
  • DSG1
view
Q07157 Tight junction protein 1
  • TJP1
  • ZO1
view
Q14126 Desmoglein-2
  • CDHF5
  • DSG2
view
Q16625 Occludin
  • OCLN
view
Q9UDY2 Tight junction protein ZO-2
  • TJP2
  • X104
  • ZO2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025