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Amino acid transport across the plasma membrane

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-352230

PubChem

R-HSA-352230

Description

Amino acid transport across plasma membranes is critical to the uptake of these molecules from the gut, to their reabsortion in the kidney proximal tubulues, and to their distribution to cells in which they are required for the synthesis of proteins and of amino acid derived small molecules such as neurotransmitters. Physiological studies have defined 18 "systems" that mediate amino acid transport, each characterized by its amino acid substrates, as well as its pH sensitivity and its association (or not) with ion transport. More recently, molecular cloning studies have allowed the identification of the plasma membrane transport proteins that mediate these reactions. Amino acid uptake mediated by 17 of these transporters is annotated here (Broer 2008).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 24 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O75387	Large neutral amino acids transporter small subunit 3	LAT3 PB39 POV1 SLC43A1	view
P08195	Amino acid transporter heavy chain SLC3A2	MDU1 SLC3A2	view
P30825	High affinity cationic amino acid transporter 1	ATRC1 ERR REC1L SLC7A1	view
P31641	Sodium- and chloride-dependent taurine transporter	SLC6A6	view
P43007	Neutral amino acid transporter A	ASCT1 SATT SLC1A4	view
P48065	Sodium- and chloride-dependent betaine transporter	BGT1 SLC6A12	view
Q01650	Large neutral amino acids transporter small subunit 1	CD98LC LAT1 MPE16 SLC7A5	view
Q07837	Amino acid transporter heavy chain SLC3A1	NBAT SLC3A1	view
Q15758	Neutral amino acid transporter B(0)	ASCT2 M7V1 RDR RDRC SLC1A5	view
Q695T7	Sodium-dependent neutral amino acid transporter B(0)AT1	B0AT1 SLC6A19	view

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