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Chemokine receptors bind chemokines

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-380108

PubChem

R-HSA-380108

Description

Chemokine receptors are cytokine receptors found on the surface of certain cells, which interact with a type of cytokine called a chemokine. Following interaction, these receptors trigger a flux of intracellular calcium which leads to chemotaxis. Chemokine receptors are divided into different families, CXC chemokine receptors, CC chemokine receptors, CX3C chemokine receptors and XC chemokine receptors that correspond to the 4 distinct subfamilies of chemokines they bind.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 26 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O00421	C-C chemokine receptor-like 2	CCR11 CCR6 CCRL2 CKRX CRAM HCR	view
O00574	C-X-C chemokine receptor type 6	BONZO CXCR6 STRL33 TYMSTR	view
O00590	Atypical chemokine receptor 2	ACKR2 CCBP2 CCR10 CMKBR9 D6	view
P13500	C-C motif chemokine 2	CCL2 MCP1 SCYA2	view
P13501	C-C motif chemokine 5	CCL5 D17S136E SCYA5	view
P22362	C-C motif chemokine 1	CCL1 SCYA1	view
P25024	C-X-C chemokine receptor type 1	CMKAR1 CXCR1 IL8RA	view
P25025	C-X-C chemokine receptor type 2	CXCR2 IL8RB	view
P25106	Atypical chemokine receptor 3	ACKR3 CMKOR1 CXCR7 GPR159 RDC1	view
P32246	C-C chemokine receptor type 1	CCR1 CMKBR1 CMKR1 SCYAR1	view

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