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MIRAGE
G alpha (q) signalling events

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Heterotrimeric G-protein Gq/11 (inactive)Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive)Ligand:GPCR complexes that activate Gq/11GDPGTPLigand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active)Ligands of GPCRs that activate Gq/11GPCRs that activate Gq/11G-protein beta-gamma complexG-protein alpha (q/11): GTPGRK2G-protein alpha (q):GRK2G-protein alpha (q):GRK5GRK5G-protein alpha (q/11):Trio family RhoGEFsTRIO family RhoGEFsPLC-betaPLC beta:G alpha (q/11)G-protein alpha (q/11):PI3K alphaPI3K alphaG-protein alpha (q/11):GDPBTKActive Gq:BTKActive Gq:Active BTKBTK_HUMANRGS1,2,3,4,5,13,16,17,18,19,21G alpha (q):GTP:RGSG alpha (q):GDP:RGSPiPLC-beta:G-alpha(q/11):PIP2PLC-beta:G-alpha(q/11):DAG:IP3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 1 - 10 of 110 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O00254 Proteinase-activated receptor 3
  • F2RL2
  • PAR3
 view
O00398 Putative P2Y purinoceptor 10
  • P2RY10
 view
O14842 Free fatty acid receptor 1
  • FFAR1
  • GPR40
 view
O14843 Free fatty acid receptor 3
  • FFAR3
  • GPR41
 view
O15552 Free fatty acid receptor 2
  • FFA2
  • FFAR2
  • GPCR43
  • GPR43
 view
O43193 Motilin receptor
  • GPR38
  • MLNR
  • MTLR
  • MTLR1
 view
O43194 G-protein coupled receptor 39
  • GPR39
 view
O43613 Orexin/Hypocretin receptor type 1
  • HCRTR1
 view
O43614 Orexin receptor type 2
  • HCRTR2
 view
O60229 Kalirin
  • DUET
  • DUO
  • HAPIP
  • KALRN
  • TRAD
 view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025